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Spectral study of light dosimetry for clinical LLT based on a simplified one-dimensional model of a two-layered medium analyzed within the limits of Kubelka-Munk approximation is presented. The relationship between the surface irradiance and the fluence rate seeing by a target at a given depth in tissues is studied for various irradiating wavelengths. The behavior of the fluence rate is also examined as a function of a blood volume fraction in tissues. Strong dependence of the fluence rate in skin on irradiating wavelengths has found in visible spectrum from about 600nm to about 800nm. In contrast, the fluence rate does not change much over the near infrared region from 800nm t0 1,300nm. Spectral dosimetry in blood content muscles exhibits progressive increase of the fluence rate over visible and near infrared ranges. It has shown that blood perfusion of tissues differently affects the fluence rate at various wavelengths. The discussed model allows estimation of the surface irradiance required to provide the therapeutic value of the fluence
rate at a target.
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Valentin Grimblatov, Alexander Rubinshtein, Marina Rubinshtein, "Spectral dosimetry in low light therapy," Proc. SPIE 6140, Mechanisms for Low-Light Therapy, 61400S (28 February 2006); https://doi.org/10.1117/12.659703