Optimization of line-field spectral domain optical coherence tomography for in vivo high-speed 3D retinal imaging

Yoshifumi Nakamura; Shuichi Makita; Masahiro Yamanari; Yoshiaki Yasuno; Masahide Itoh; Toyohiko Yatagai

doi:10.1117/12.702643

7 February 2007 Optimization of line-field spectral domain optical coherence tomography for in vivo high-speed 3D retinal imaging

Yoshifumi Nakamura, Shuichi Makita, Masahiro Yamanari, Yoshiaki Yasuno, Masahide Itoh, Toyohiko Yatagai

Author Affiliations +

Proceedings Volume 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI; 64291P (2007) https://doi.org/10.1117/12.702643
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Line-field spectral domain optical coherence tomography (LF-SDOCT), which is a parallel detection OCT technique that provides single cross-sectional image without mechanical scanning, has been developed for very high-speed three-dimensional (3D) imaging of human retina in vivo. By optimizing the integration time of the camera for the sample motion, we have successfully performed the in vivo 3D retinal imaging, which is sufficiently free from the motion artifact. The achievable A-lines rate is 54.4 kHz A-lines/s with the maximum sensitivity of 89.4 dB, and it corresponds to more than 2 times higher speed than conventional flying spot SD-OCT system. The in vivo 3D retinal measurement with the 256 cross-sectional images (528 A-lines/image) was successfully performed at 2.5 seconds.

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Yoshifumi Nakamura, Shuichi Makita, Masahiro Yamanari, Yoshiaki Yasuno, Masahide Itoh, and Toyohiko Yatagai "Optimization of line-field spectral domain optical coherence tomography for in vivo high-speed 3D retinal imaging", Proc. SPIE 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI, 64291P (7 February 2007); https://doi.org/10.1117/12.702643

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