Application of fluorescence labeled liposome nanoparticles in the cell imaging

Jianbing Hu; Huimin Li; Xiaoxiao He; Ping Gong; Kemin Wang; Shouchun Zhang

doi:10.1117/12.741590

10 May 2007 Application of fluorescence labeled liposome nanoparticles in the cell imaging

Jianbing Hu, Huimin Li, Xiaoxiao He, Ping Gong, Kemin Wang, Shouchun Zhang

Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 65341K (2007) https://doi.org/10.1117/12.741590
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China

Abstract

Fluorescence labeled liposome nanoparticles were prepared by dispersion of film method. The size of nanoparticles was around 50 nm. DPPE-FITC synthesized in our lab was used to label the liposome nanoparticles. Anti-cytokeratins 19 antibody was connected to the surface of the fluorescence liposome nanoparticles. After incubation with MGC cells and COS-7 cells for 30 min, MGC cells were selectively recognized by anti-cytokeratins 19 antibody modified liposome nanoparticles and well imaged under laser confocal microscope. This fluorescence labeled liposome nanoparticles is expected to have good applications in cell recognition and tumor diagnosis.

Citation Download Citation

Jianbing Hu, Huimin Li, Xiaoxiao He, Ping Gong, Kemin Wang, and Shouchun Zhang "Application of fluorescence labeled liposome nanoparticles in the cell imaging", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65341K (10 May 2007); https://doi.org/10.1117/12.741590

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