In vitro study of indocyanine green solution interaction with skin

Elina A. Genina; Marina Yu. Kuzmina; Stanislav S. Pankov; Alexey N. Bashkatov; Valery V. Tuchin

doi:10.1117/12.740992

26 April 2007 In vitro study of indocyanine green solution interaction with skin

Elina A. Genina, Marina Yu. Kuzmina, Stanislav S. Pankov, Alexey N. Bashkatov, Valery V. Tuchin

Proceedings Volume 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII; 65351H (2007) https://doi.org/10.1117/12.740992
Event: Saratov Fall Meeting 2006, 2006, Saratov, Russian Federation

Abstract

Absorption properties of Indocyanine Green (ICG) dissolved in both water and 40%-ethanol for potential using in laser selective thermolysis have been researched. Correlation between magnitudes and positions of absorption bands of ICG in dependence on the kind of solvent and concentration of ICG has been studied. Interaction between ICG solutions and rat skin in vitro has been investigated. Shift of the main absorption peaks of ICG solutions in skin has been defined. Such shift is caused by ICG interaction with protein molecules of the stratum corneum and dermis. Diffusion coefficients of ICG in skin have been estimated at diffusion of aqueous solutions through dermis and at diffusion of alcohol solutions through both dermis and epidermis as (7.70±2.51)×10^-7, (18.79±3.35)×10^-7 and (6.85±3.75)×10^-7, respectively.

Citation Download Citation

Elina A. Genina, Marina Yu. Kuzmina, Stanislav S. Pankov, Alexey N. Bashkatov, and Valery V. Tuchin "In vitro study of indocyanine green solution interaction with skin", Proc. SPIE 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, 65351H (26 April 2007); https://doi.org/10.1117/12.740992

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available