Meta-analysis on intravascular low energy laser therapy

Shu-Dong Zhao; Timon Cheng-Yi Liu; Yan-Fang Wang; Song-Hao Liu

doi:10.1117/12.823336

6 March 2009 Meta-analysis on intravascular low energy laser therapy

Shu-Dong Zhao, Timon Cheng-Yi Liu, Yan-Fang Wang, Song-Hao Liu

Proceedings Volume 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine; 728012 (2009) https://doi.org/10.1117/12.823336
Event: Photonics and Optoelectronics Meetings, 2008, Wuhan, China

Abstract

Intravascular low energy laser therapy (ILELT) was put forward for cardiocirculatory diseases in USA in 1982, was popular in Russia in 1980s, and then in China in 1990s. The therapeutic effects of ILELT and drugs in comparison with drugs only on Chinese patients and their blood parameters were analyzed with meta-analyses and reported as (OR, 95%CI) for patient improvement and (WMD, 95% CI) for blood parameter improvement, where 95%CI, OR and WMD denoted 95% confidence intervals, odds ratio and weighted mean difference, respectively. It was found that the patients of cerebral infarction (2.39, 2.09~2.74) and cerebrovascular diseases (2.97, 1.69~2.53) were cured, respectively, (P < 0.01), and the symptom improvement of patients of cerebral infarction, cerebrovascular diseases and diabetes were significant (3.13, 2.79~3.51), (4.92, 3.39~7.14) , and (3.80, 2.79~5.18), and mild (3.66, 3.15~4.24), (4.95, 2.77~8.84), and (7.11, 4.54~11.13), respectively, (P < 0.01). It was also found that the blood parameters such as cholesterol (-0.78, -1.32~-0.24), total cholesterol (-1.08, -1.80~-0.36), low density lipoprotein cholesterol (-0.6, -1.01~-0.19), triacylglycerol (0.63, -0.83~-0.42), high density lipoprotein (0.34, 0.10~0.59), erythrocyte aggregation index (-0.24, -0.27~-0.21), erythrocyte Sedimentation Rate (-4.57, -7.26~-1.89), fibrinogen (-0.76, -1.31~-0.21), whole blood contrast viscosity (-0.40, -0.69~-0.12), low cut blood viscosity (-1.2, -1.93~-0.48), high cut blood viscosity (-0.62, -0.92~-0.32), whole blood viscosity(-1.2, -1.85~-0.54) and plasma blood contrast viscosity(-0.07, -0.12~-0.03) were found improved (P < 0.05). It is concluded that the patients of cerebral infarction, cerebrovascular diseases and diabetes might be improved with ILELT, which might be mediated by blood parameter improvement.

Citation Download Citation

Shu-Dong Zhao, Timon Cheng-Yi Liu, Yan-Fang Wang, and Song-Hao Liu "Meta-analysis on intravascular low energy laser therapy", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 728012 (6 March 2009); https://doi.org/10.1117/12.823336

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