In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Jiechen Yin; Gangjun Liu; Jun Zhang; Lingfeng Yu; Sari Mahon; David Mukai; Matthew Brenner; Zhongping Chen

doi:10.1117/12.841346

19 February 2010 In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Jiechen Yin, Gangjun Liu, Jun Zhang, Lingfeng Yu, Sari Mahon, David Mukai, Matthew Brenner, Zhongping Chen

Author Affiliations +

Proceedings Volume 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV; 755408 (2010) https://doi.org/10.1117/12.841346
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We report on the feasibility of rapid, high resolution, 3-dimensional swept source optical coherence tomography (3D SSOCT) to detect early airway injury changes following smoke inhalation exposure in a rabbit model. The SSOCT system obtains 3-D helical scanning using a microelectromechanical system (MEMS) motor based endoscope. Real-time 2-D data processing and image display at the speed of 20 frames per second are achieved by adopting the technique of shared-memory parallel computing. Longitudinal images are reconstructed via an image processing algorithm to remove motion artifacts caused by ventilation and pulse. We demonstrate the ability of the SSOCT system to detect increases in tracheal and bronchial airway thickness that occurs shortly after smoke exposure.

Citation Download Citation

Jiechen Yin, Gangjun Liu, Jun Zhang, Lingfeng Yu, Sari Mahon, David Mukai, Matthew Brenner, and Zhongping Chen "In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography", Proc. SPIE 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, 755408 (19 February 2010); https://doi.org/10.1117/12.841346

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available