Noninvasive blood glucose sensing on human body with near-infrared reflection spectroscopy

Zhen-hao Huang; Chang-ning Hao; Lin-lin Zhang; Yan-chao Huang; Yi-qin Shi; Geng-ru Jiang; Jun-li Duan

doi:10.1117/12.900160

8 September 2011 Noninvasive blood glucose sensing on human body with near-infrared reflection spectroscopy

Zhen-hao Huang, Chang-ning Hao, Lin-lin Zhang, Yan-chao Huang, Yi-qin Shi, Geng-ru Jiang, Jun-li Duan

Proceedings Volume 8193, International Symposium on Photoelectronic Detection and Imaging 2011: Advances in Infrared Imaging and Applications; 81931O (2011) https://doi.org/10.1117/12.900160
Event: International Symposium on Photoelectronic Detection and Imaging 2011, 2011, Beijing, China

Abstract

The non-invasive blood glucose sensing method has shown its high impact on the clinic application. This can make the measurement on the clinically relevant concentrations of glucose be free from the pain of patient. The transmission spectrum study indicates that the dependence of glucose concentration on the absorbance is in linear manner for the glucose concentration in the region of 30mg/dL to 4.5×10⁴mg/dL. By the near infrared reflection spectroscopy of fiber spectrometer, the reflection band between 1.2μm and 1.35μm can be used to correlated with the glucose concentration in the range of 30 to 300 mg/dL. This reflection band is finally used to measure the glucose concentration effect in non-invasive manner, which gives the statistical significance of P value 0.02. Our experiment result shows that it is possible to get the glucose concentration by the near infrared reflection spectrum measurement on the human forefinger. This non-invasive blood glucose sensing method may useful in clinic after more experiment for different people.

Citation Download Citation

Zhen-hao Huang, Chang-ning Hao, Lin-lin Zhang, Yan-chao Huang, Yi-qin Shi, Geng-ru Jiang, and Jun-li Duan "Noninvasive blood glucose sensing on human body with near-infrared reflection spectroscopy", Proc. SPIE 8193, International Symposium on Photoelectronic Detection and Imaging 2011: Advances in Infrared Imaging and Applications, 81931O (8 September 2011); https://doi.org/10.1117/12.900160

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