Characterization of muscle stretching and damage using polarization-sensitive optical coherence tomography (PS-OCT)

Dongsheng Chen; Nan Zeng; Celong Liu; Hui Ma

doi:10.1117/12.999951

11 December 2012 Characterization of muscle stretching and damage using polarization-sensitive optical coherence tomography (PS-OCT)

Dongsheng Chen, Nan Zeng, Celong Liu, Hui Ma

Author Affiliations +

Proceedings Volume 8553, Optics in Health Care and Biomedical Optics V; 85533C (2012) https://doi.org/10.1117/12.999951
Event: Photonics Asia, 2012, Beijing, China

Abstract

In this paper, we study muscle elastic drawing and damage using our lab’s polarization-sensitive optical coherence tomography (PS-OCT) instrument and polarization sensitive Monte Carlo program. First, we acquire two-dimensional PS-OCT images of elastically drawn and injured muscle, injury processes including dehydration and hydrolysis, we extract some characteristics from experimental results including extinction coefficient, integral reflectivity and birefringence and so on, which will change during muscle is being elastically drawn or injured. In order to further understand and evaluate the degree of muscle elastic drawing or damage according to the measurements parameters mentioned above, we do some corresponding simulations using our lab’s Monte Carlo program, which is based on a sphere cylinder birefringence model and can simulate complicated tissue containing anisotropic microstructures and various polarization imaging and measurement systems. For muscle elastic drawing, we find that integral reflectivity sometimes increases and decreases as muscle’s elastic drawing continues, and through simulation we are unable to find the relationship between extinction coefficients and muscle elastic drawing. As for muscle damage, we simulate two processes: dehydration and hydrolysis. We find that as dehydration deepens, the birefringence of muscle is increasing but getting slowly and the integral reflectivity is decreasing, and as hydrolysis deepens, the birefringence decreases and the integral reflectivity decreases almost linearly. Through the analysis above, we demonstrate the validity of those parameters to characterize muscle elasticity and fiber structure and explain its potential for assessment of muscle damage.

Citation Download Citation

Dongsheng Chen, Nan Zeng, Celong Liu, and Hui Ma "Characterization of muscle stretching and damage using polarization-sensitive optical coherence tomography (PS-OCT)", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85533C (11 December 2012); https://doi.org/10.1117/12.999951

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