Special antitumor immune effects of laser immunotherapy with SWNT-GC

Feifan Zhou; Sheng Song; Wei R. Chen

doi:10.1117/12.2042372

27 February 2014 Special antitumor immune effects of laser immunotherapy with SWNT-GC

Feifan Zhou, Sheng Song, Wei R. Chen

Proceedings Volume 8944, Biophotonics and Immune Responses IX; 89440J (2014) https://doi.org/10.1117/12.2042372
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

In our previous work, we constructed a multifunction nano system SWNT-GC, which can synergize photothermal and immunological effects. To further improve the application of this system, we study the cytotoxicity of SWNT-GC and investigate the effects on malignant tumor therapy. Here, we selected the optimal concentration of GC and SWNTs for the stable SWNT-GC construction. No cytotoxicity was observed under the dose used in the experiments. Using mouse melanoma tumor model, Laser+SWNT-GC treatment resulted in a significant mice survival rate, there were no long-term survivors under other treatment. It is providing a promising treatment modality for the malignancy.

Citation Download Citation

Feifan Zhou, Sheng Song, and Wei R. Chen "Special antitumor immune effects of laser immunotherapy with SWNT-GC", Proc. SPIE 8944, Biophotonics and Immune Responses IX, 89440J (27 February 2014); https://doi.org/10.1117/12.2042372

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