CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12144 > Article
Presentation
30 May 2022 In vivo biophotonic analysis of preimplantation embryonic development
Irina V. Larina
Author Affiliations +
Proceedings Volume PC12144, Biomedical Spectroscopy, Microscopy, and Imaging II; PC121440Y (2022) https://doi.org/10.1117/12.2626872
Event: SPIE Photonics Europe, 2022, Strasbourg, France
Abstract
Trough intravital functional optical coherence tomography (OCT) in mouse models, this study investigates physiological processes within the fallopian tube in vivo. The transport of oocytes and embryos through the oviduct (fallopian tube) is a fundamental reproductive processes of clinical importance. However, because mammalian fertilization and embryogenesis take place deep within the female body, these processes are hidden from direct observation. Therefore, much of what we know about the innerworkings of the female reproductive tract is extrapolated from in vitro and ex vivo experimental settings and does not necessarily represent the native state, limiting success in management of reproductive disorders. This study presents first in vivo volumetric dynamic imaging of oocytes and embryos as they are transported through the mouse oviduct. By implementation of new functional OCT methods, we established methods for tracking oviductal ciliary function and individual sperm movements. Supported by dynamic volumetric visualizations, the study reveals a variety of intriguing never-before-seen dynamic behaviors and suggest new regulatory mechanisms driving reproductive processes.
Conference Presentation
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Irina V. Larina "In vivo biophotonic analysis of preimplantation embryonic development", Proc. SPIE PC12144, Biomedical Spectroscopy, Microscopy, and Imaging II, PC121440Y (30 May 2022); https://doi.org/10.1117/12.2626872
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
In vivo imaging
Biological research
Biomedical optics
Optical coherence tomography
Fallopian tube
In vitro testing
Mouse models
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top