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17 March 2023 A whole-head ultra-high density diffuse optical tomography system for functional human brain mapping
Morgan Fogarty, Sean M. Rafferty, Anthony C. O'Sullivan, Calamity F. Svoboda, Zachary E. Markow, Edward J. Richter, Tessa George, Kelsey King, Dana Wilhelm, Kalyan Tripathy, Jason W. Trobaugh, Adam T. Eggebrecht, Joseph P. Culver
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Proceedings Volume PC12365, Neural Imaging and Sensing 2023; PC1236501 (2023) https://doi.org/10.1117/12.2649118
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
High-Density Diffuse Optical Tomography (HD-DOT) is an emerging modality that uses a dense array of overlapping measurements that provides image quality validated against fMRI. Here, we doubled the optode density of our previously reported HD-DOT system, expanded the field of view and achieve higher resolution and image quality. Task-based and movie viewing activation maps reveal strong contrast to noise of cortical function across these tasks. Additionally, we show the expanded field of view covers functional networks not available with our previously reported HD-DOT system. This system is promising for future studies using resting state functional connectivity, decoding, and naturalistic paradigms.
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Morgan Fogarty, Sean M. Rafferty, Anthony C. O'Sullivan, Calamity F. Svoboda, Zachary E. Markow, Edward J. Richter, Tessa George, Kelsey King, Dana Wilhelm, Kalyan Tripathy, Jason W. Trobaugh, Adam T. Eggebrecht, and Joseph P. Culver "A whole-head ultra-high density diffuse optical tomography system for functional human brain mapping", Proc. SPIE PC12365, Neural Imaging and Sensing 2023, PC1236501 (17 March 2023); https://doi.org/10.1117/12.2649118
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KEYWORDS
Brain mapping
Diffuse optical tomography
Image quality
Optical imaging
Optical arrays
Optical components
Optical resolution
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