CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12379 > Article
Presentation
9 March 2023 Assessment of prostate cancer progression using a translational needle photoacoustic sensing probe: preliminary study with intact human prostates ex-vivo
Linyu Ni, Wei-Kuan Lin, Amy Kasputis, Deborah Postiff, Javed Siddiqui, Matthew Allaway, Matthew S. Davenport, John T. Wei, Jay L. Guo, Todd M. Morgan, Aaron M. Udager, Xueding Wang, Guan Xu
Author Affiliations +
Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC1237908 (2023) https://doi.org/10.1117/12.2649301
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
In this study, we developed a prototype interstitial all-optical needle photoacoustic sensing probe for clinical translation of prostate cancer. The performance of the PA needle probe was examined on intact human prostates ex vivo to simulate the transrectal ultrasound (US) guided transperineal prostate biopsy procedures. Analysis based on PA spectrum analysis in 8-28 MHz range of acquired RF signals at multi-wavelengths shows statistical difference between benign and cancerous regions (n=49, p<0.05). Multivariate SVM analysis using linear and midbandfit parameters can obtain an accuracy close to 90%.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Linyu Ni, Wei-Kuan Lin, Amy Kasputis, Deborah Postiff, Javed Siddiqui, Matthew Allaway, Matthew S. Davenport, John T. Wei, Jay L. Guo, Todd M. Morgan, Aaron M. Udager, Xueding Wang, and Guan Xu "Assessment of prostate cancer progression using a translational needle photoacoustic sensing probe: preliminary study with intact human prostates ex-vivo", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC1237908 (9 March 2023); https://doi.org/10.1117/12.2649301
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Prostate
Photoacoustic spectroscopy
Prostate cancer
Fiber optics
Optical fibers
Principal component analysis
Prototyping
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top