Presentation
13 March 2024 Dynamic OCT for in vivo cilia metachronal wave analysis in the mouse fallopian tube
Author Affiliations +
Abstract
Motile cilia lining the lumen of the Fallopian tube (oviduct) are known to play an essential role in reproduction; however, how their specific roles are not understood. Here, we present a novel dynamic OCT method for imaging of waves propagating along the epithelial surfaces created by the beating cilia (metachronal waves). The method is based on spatiotemporal mapping of the phase of ciliary beat calculated based on intensity fluctuations in OCT images. This method was applied in vivo to visualize and quantify cilia metachronal waves within the mouse fallopian tube in vivo, volumetrically, through the tissue layers.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Tian Xia, Shang Wang, and Irina V. Larina "Dynamic OCT for in vivo cilia metachronal wave analysis in the mouse fallopian tube", Proc. SPIE PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI, PC1284102 (13 March 2024); https://doi.org/10.1117/12.3006504
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KEYWORDS
In vivo imaging

Optical coherence tomography

Fallopian tube

Reproductive system

Visualization

Genetics

Mouse models

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