CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12855 > Article
Presentation
13 March 2024 Single pulse stimulated Raman photothermal (spSRP) microscopy using an OPA
Yifan Zhu, Hongli Ni, Ji-Xin Cheng
Author Affiliations +
Proceedings Volume PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024; PC1285515 (2024) https://doi.org/10.1117/12.3001791
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Stimulated Raman photothermal (SRP) is a newly developed chemical imaging scheme that probes the SRS induced thermal effect with a third laser beam. SRP shows high sensitivity, where a >500-fold boost of modulation depth comparing to SRS has been achieved. To further improve the sensitivity of SRP, we introduce spSRP with a ~1 MHz repetition rate, high peak power OPA laser serving as the SRP excitation source. The high peak power increases the energy deposition of SRS process, enables SRP measurement with a single pair of pump and Stokes laser pulses. spSRP is a firm step towards vibrational spectroscopic imaging with ultrahigh sensitivity.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Yifan Zhu, Hongli Ni, and Ji-Xin Cheng "Single pulse stimulated Raman photothermal (spSRP) microscopy using an OPA", Proc. SPIE PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC1285515 (13 March 2024); https://doi.org/10.1117/12.3001791
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Imaging spectroscopy
Microscopy
Raman spectroscopy
Modulation
Pulse signals
Pulsed laser operation
Signal intensity
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top