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1 March 2008 Sentinel lymph node detection ex vivo using ultrasound-modulated optical tomography
Chulhong Kim, Kwanghyun Song, Lihong V. Wang
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Journal of Biomedical Optics, Vol. 13, Issue 2, 020507 (March 2008). https://doi.org/10.1117/1.2907791
Abstract
We apply ultrasound-modulated optical tomography (UOT) to image ex-vivo methylene-blue-dyed sentinel lymph nodes embedded in 3.2-cm-thick chicken breast tissues. The UOT system is implemented for the first time using ring-shaped light illumination, intense acoustic bursts, and charge-coupled device (CCD) camera-based speckle contrast detection. Since the system is noninvasive, nonionizing, portable, relatively cost effective, and easy to combine with photoacoustic imaging and single element ultrasonic pulse-echo imaging, UOT can potentially be a good imaging modality for the detection of sentinel lymph nodes in breast cancer staging in vivo.
©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Chulhong Kim, Kwanghyun Song, and Lihong V. Wang "Sentinel lymph node detection ex vivo using ultrasound-modulated optical tomography," Journal of Biomedical Optics 13(2), 020507 (1 March 2008). https://doi.org/10.1117/1.2907791
Published: 1 March 2008
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Cited by 11 scholarly publications and 1 patent.
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KEYWORDS
Ultrasound-modulated optical tomography
Imaging systems
Lymphatic system
Ultrasonography
Tissues
CCD cameras
Breast
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