Open Access
1 July 2008 Monkey brain cortex imaging by photoacoustic tomography
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Abstract
Photoacoustic tomography (PAT) is applied to image the brain cortex of a monkey through the intact scalp and skull ex vivo. The reconstructed PAT image shows the major blood vessels on the monkey brain cortex. For comparison, the brain cortex is imaged without the scalp, and then imaged again without the scalp and skull. Ultrasound attenuation through the skull is also measured at various incidence angles. This study demonstrates that PAT of the brain cortex is capable of surviving the ultrasound signal attenuation and distortion caused by a relatively thick skull.
©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
Xinmai Yang and Lihong V. Wang "Monkey brain cortex imaging by photoacoustic tomography," Journal of Biomedical Optics 13(4), 044009 (1 July 2008). https://doi.org/10.1117/1.2967907
Published: 1 July 2008
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CITATIONS
Cited by 84 scholarly publications.
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KEYWORDS
Skull

Brain

Acquisition tracking and pointing

Neuroimaging

Signal detection

Bone

Ultrasonography

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