KEYWORDS: Picture Archiving and Communication System, Molecular imaging, Preclinical imaging, Data archive systems, Human-machine interfaces, Data conversion, Radiology, Data storage, Standards development, Pre-clinical research
Advances in biology, computer technology and imaging technology have given rise to a scientific specialty referred to as
molecular imaging, which is the in vivo imaging of cellular and molecular pathways using contrast-enhancing targeting
agents. Increasing amounts of molecular imaging research are being performed at pre-clinical stages, generating diverse
datasets that are unstructured and thereby lacking in archiving and distribution solutions. Since PACS in radiology is a
mature clinical archiving solution, a method is proposed to convert current imaging files from preclinical molecular
imaging studies into DICOM formats for archival and retrieval from PACS systems. A web-based DICOM gateway is
presented with an emphasis on metadata mapping in the DICOM header, system connectivity, and overall user
workflow. This effort to conform preclinical imaging data to the DICOM standard is necessary to utilize current PACS
solutions for preclinical imaging data content archiving and distribution.
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