As the primary tool for studying cells and biological tissues, micro-imaging technology has significantly promoted the bio-medical development. The microscopic ghost imaging system is designed to meet the diverse needs of microscopy imaging. In this method, the original optical path of a research-grade upright fluorescence microscope was modified to be an optical path of ghost imaging. Three different matrixes were adopted as the preset pattern of the digital micromirror device. The experimental results demonstrate that the gold matrix can obtain a relatively perfect result under weak and unstable lighting conditions. This method is expected to promote the application of ghost imaging technology in microscopy imaging of cells and biological tissues.
KEYWORDS: Photodynamic therapy, Tumors, In vivo imaging, Cancer, Quantum dots, Organisms, Femtosecond phenomena, Biomedical optics, Absorption, Resonance energy transfer
Recently, near-infrared (NIR) excitation has been suggested for PDT improvement and therapy of cancer.In this study, 5-aminolevulinic acid (ALA), a kind of photosensitizer, were coordinated to CuInS2/ZnS QDs to form the CuInS2/ZnS-ALA conjugates. An efficient transfer of energy from the donor (QDs) to the acceptor (ALA) was demonstrated through forster resonance energy transfer (FRET). The treatment effects of the conjugates in vivo was confirmed under 1300nm femtosecond laser. The results demonstrate that the CuInS2/ZnS-ALA conjugates are promising for PDT and can be used in imaging and biomedical field.
The laser pulse broadening and delay caused by cloud and aerosol can degrade the data transmission rate. The pulse broadening and the time delay induced by atmosphere channel are analyzed. Then the corresponding performance of communication rate for DSOC system which based on PPM scheme are investigated.In this paper, both the pulse broadening caused by cloud, aerosol and atmospheric turbulence and the time delay induced by turbulence are analyzed. Then the corresponding performance of communication rate for DSOC system which based on PPM scheme are investigated. Numerical results indicate that the cloud physical thickness and aerosol particle optical thickness can affect the communication rate severely. But, the rate can be improved by choosing lower modulation order and initial pulse width under clear atmosphere condition. The results enable us to determine suitable parameters in practical applications for better communication rate.
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