Ms. Hannah Wang Profile

Hannah Wang

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 10 September 2019 Paper

Deformable and reconfigurable mouse phantoms with 3D printing and LTS technologies

Hannah Wang, Mengzhou Li, Matthew Getzin, Brigitte Arduini, Nathaniel Covert, Deepak Vashishth, Paul Fitzgerald

Proceedings Volume 11113, 111131S (2019) https://doi.org/10.1117/12.2530770

KEYWORDS: Tissues, Signal attenuation, 3D printing, Skin, 3D modeling, X-rays, Liver, Polymethylmethacrylate, Polyurethane, Scanners

Read Abstract +

Mice are used for models of almost all human diseases and are routinely scanned by micro-CT scanners. Mouse phantoms are often used for image-quality assessment. With recent developments in deep-learning-based preclinical imaging, there is a major need for large micro-CT datasets in which ground truth is known. In this study, we investigate the feasibility of making cost-effective deformable and reconfigurable mouse phantoms to generate real micro-CT datasets that reflect realistic underlying physical characteristics. Such datasets are highly desirable; for example, complicated photon-counting micro-CT datasets are needed for deep-learning-based material decomposition. In our scheme, mouse body parts are 3Dprinted with high precision using rigid or flexible materials. Liquid tissue surrogates (LTSs) or bioinks/cell lines could be used to emulate mouse organs and physiological fluid in the animals. LTSs provide realistic x-ray properties of their biological counterparts. The LTS organs could be contained in not only 3D-printed chambers, but also dialysis tubing, which emulates the cell membrane. Furthermore, through bioprinting and tissue engineering, organs and tissues can be made even more realistic for micro-CT and other types of tomographic scanning.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years