Dr. Henryk Szmacinski Profile

Dr. Henryk Szmacinski

Principal Scientist at Univ of Maryland School of Medicine

SPIE Involvement:

Author

Publications (25)

SPIE Journal Paper | 21 April 2020 Open Access

Imaging hydroxyapatite in sub-retinal pigment epithelial deposits by fluorescence lifetime imaging microscopy with tetracycline staining

Henryk Szmacinski, Kavita Hegde, Hui-Hui Zeng, Katayoun Eslami, Adam Puche, Imre Lengyel, Richard B. Thompson

JBO, Vol. 25, Issue 04, 047001, (April 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.4.047001

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Modulation, Retina, Phase shift keying, Microscopy, Tissues, Bone, Eye, Data modeling

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Proceedings Article | 12 February 2018 Presentation + Paper

Towards early detection of age-related macular degeneration with tetracyclines and FLIM

Henryk Szmacinski, Kavita Hegde, Hui-Hui Zeng, Katayoun Eslami, Adam Puche, Joseph Lakowicz, Imre Lengyel, Richard Thompson

Proceedings Volume 10484, 1048409 (2018) https://doi.org/10.1117/12.2303768

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Retina, Modulation, Microscopy, Eye, In vivo imaging, Data modeling

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SPIE Journal Paper | 25 April 2014 Open Access

Application of phasor plot and autofluorescence correction for study of heterogeneous cell population

Henryk Szmacinski, Vladimir Toshchakov, Joseph Lakowicz

JBO, Vol. 19, Issue 04, 046017, (April 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.4.046017

KEYWORDS: Fluorescence lifetime imaging, Fluorescence resonance energy transfer, Proteins, Luminescence, Modulation, Data corrections, Data modeling, Molecules, Fluorescent proteins, Receptors

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Proceedings Article | 3 March 2010 Paper

Metal-enhanced intrinsic fluorescence of proteins and label-free bioassays

Krishanu Ray, Henryk Szmacinski, Mustafa Chowdhury, Joseph Lakowicz

Proceedings Volume 7577, 75770K (2010) https://doi.org/10.1117/12.840412

KEYWORDS: Proteins, Luminescence, Aluminum, Quartz, Metals, Nanostructuring, Nanostructures, Scanning electron microscopy, Ultraviolet radiation, Gold

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Proceedings Article | 21 February 2008 Paper

Single molecule photophysics near metallic nanostructures

Jian Zhang, Yi Fu, Krishanu Ray, Mustafa Chowdhury, Henryk Szmacinski, Kazimierz Nowaczyk, Joseph Lakowicz

Proceedings Volume 6862, 68620S (2008) https://doi.org/10.1117/12.770381

KEYWORDS: Metals, Particles, Silver, Luminescence, Molecules, Atmospheric particles, Finite-difference time-domain method, Nanoparticles, Fluorescence resonance energy transfer, Plasmons

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Proceedings Article | 21 February 2008 Paper

Measurement and monitoring of the production of proteins during cell culture using plasmonic structures

Henryk Szmacinski, Derek Smith, Michael Hanson, Govind Rao, Joseph Lakowicz

Proceedings Volume 6869, 68690Z (2008) https://doi.org/10.1117/12.778490

KEYWORDS: Modulation, Luminescence, Phase shifts, Silver, Phase shift keying, Phase measurement, Statistical analysis, Calibration, Glasses, Proteins

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Proceedings Article | 23 February 2006 Open Access

Plasmon-controlled fluorescence: a new detection technology

Joseph Lakowicz, Mustafa Chowdhury, Krishanu Ray, Jian Zhang, Yi Fu, Ramachandram Badugu, Chandran Sabanayagam, Kazimierz Nowaczyk, Henryk Szmacinski, Kadir Aslan, Chris Geddes

Proceedings Volume 6099, 609909 (2006) https://doi.org/10.1117/12.673106

KEYWORDS: Plasmons, Luminescence, Metals, Particles, Plasmonics, Silver, Surface plasmons, Absorption, Near field, Scattering

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Proceedings Article | 18 November 2005 Paper

Nanoshell, nanosphere, and nanowire geometries for hot spot formation in surface enhanced Raman scattering

O. Glembocki, S. Prokes, H. Szmacinski, J. Liu, F. Kub, C. Kub

Proceedings Volume 6008, 600809 (2005) https://doi.org/10.1117/12.631184

KEYWORDS: Silver, Molecules, Nanostructures, Raman scattering, Dielectrics, Raman spectroscopy, Metals, Optical spheres, Nanoparticles, Nanowires

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Proceedings Article | 31 March 2005 Paper

Enhanced fluorescence using silver nanoparticles patterned by e-beam lithography

Henryk Szmacinski, Vincent Pugh, Wayne Moore, Timothy Corrigan, Shy-Hauh Guo, Ray Phaneuf

Proceedings Volume 5703, (2005) https://doi.org/10.1117/12.592470

KEYWORDS: Luminescence, Particles, Nanoparticles, Silver, Reflectivity, Plasmons, Electron beam lithography, Atmospheric particles, Molecules, Scanning electron microscopy

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Proceedings Article | 1 July 2004 Paper

Enhanced chemical fluorescence-based sensing using metallic nano-composites

Henryk Szmacinski, Vincent Pugh, Wayne Moore, Chris Geddes, Kadir Aslan, Joseph Lakowicz

Proceedings Volume 5318, (2004) https://doi.org/10.1117/12.536415

KEYWORDS: Silver, Calcium, Nanoparticles, Luminescence, Quantum efficiency, Glasses, Absorption, Biological and chemical sensing, Silica, Silicon

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Proceedings Article | 1 May 1998 Paper

Long-lived highly luminescent rhenium (I) metal-ligand complex as a probe of biomolecules

Felix Castellano, Xiang-Qun Guo, Li Li, Henryk Szmacinski, Jeffrey Sipior, Joseph Lakowicz

Proceedings Volume 3256, (1998) https://doi.org/10.1117/12.307064

KEYWORDS: Anisotropy, Luminescence, Proteins, Quantum efficiency, Oxygen, Polarization, Rhenium, Argon, Absorption, Magnesium

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Proceedings Article | 8 May 1995 Paper

Lifetime-based sensing in highly scattering media

Henryk Szmacinski, Joseph Lakowicz

Proceedings Volume 2388, (1995) https://doi.org/10.1117/12.208549

KEYWORDS: Phase shift keying, Light scattering, Modulation, Sensors, Luminescence, Scattering media, Phase measurement, Skin, Scattering, Chemistry

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Proceedings Article | 8 May 1995 Paper

Metal-ligand complexes as a new class of long-lived fluorophores for protein hydrodynamics and fluorescence polarization immunoassay

Joseph Lakowicz, Ewald Terpetschnig, Henryk Szmacinski, Henryk Malak

Proceedings Volume 2388, (1995) https://doi.org/10.1117/12.208497

KEYWORDS: Polarization, Luminescence, Proteins, Anisotropy, Fluorescence anisotropy, Ruthenium, Diffusion, Absorption, Motion measurement, Picosecond phenomena

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Proceedings Article | 17 August 1994 Paper

Center for Fluorescence Spectroscopy: advanced studies of fluorescence dynamics, lifetime imaging, clinical sensing, two-photon excitation, and light quenching

Joseph Lakowicz, Henryk Malak, Ignacy Gryczynski, Henryk Szmacinski, Jozef Kusba, Engin Akkaya, Ewald Terpetschnig, Michael Johnson

Proceedings Volume 2137, (1994) https://doi.org/10.1117/12.182725

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Proteins, Fluorescence spectroscopy, Time resolved spectroscopy, Quenching (fluorescence), Ultraviolet radiation, Near infrared, Picosecond phenomena, Fluorescence anisotropy

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Proceedings Article | 17 August 1994 Paper

Synthesis of squaraine-N-hydroxysuccinimide esters and their biological application as long-wavelength fluorescent labels

Ewald Terpetschnig, Henryk Szmacinski, Joseph Lakowicz

Proceedings Volume 2137, (1994) https://doi.org/10.1117/12.182771

KEYWORDS: Proteins, Quantum efficiency, Luminescence, Semiconductor lasers, Fluorescent markers, Water, Absorption, Phase shift keying, Modulation, Fluorescence spectroscopy

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Proceedings Article | 21 July 1994 Paper

Emerging biomedical applications of time-resolved fluorescence spectroscopy

Joseph Lakowicz, Henryk Szmacinski, Peter Koen

Proceedings Volume 2136, (1994) https://doi.org/10.1117/12.180786

KEYWORDS: Blood, Glucose, Luminescence, Semiconductor lasers, Flow cytometry, Fluorescence lifetime imaging, Time resolved spectroscopy, Calcium, Fluorescence resonance energy transfer, Sensors

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Proceedings Article | 14 September 1993 Paper

Time-dependent photon migration imaging in two dimensions: a method for detection and localization of absorbers in tissuelike media

Eva Sevick-Muraca, Joan Frisoli, Christina Hutchinson, Henryk Szmacinski, Kazimierz Nowaczyk, Michael Johnson, Joseph Lakowicz

Proceedings Volume 1888, (1993) https://doi.org/10.1117/12.154662

KEYWORDS: Modulation, Adaptive optics, Sensors, Monte Carlo methods, Phase modulation, Photon transport, Tissue optics, Biomedical optics, Phase shift keying, Scattering

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Proceedings Article | 24 June 1993 Paper

Fluorescence-lifetime-based sensing: applications to clinical chemistry and cellular imaging

Joseph Lakowicz, Henryk Szmacinski, Richard Thompson

Proceedings Volume 1895, (1993) https://doi.org/10.1117/12.146718

KEYWORDS: Modulation, Phase shift keying, Luminescence, Calcium, Glucose, Chemistry, Diagnostics, Energy transfer, Fluorescence lifetime imaging, Blood

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Proceedings Article | 16 April 1992 Paper

Fluorescence-lifetime-based sensing of blood gases and cations

Joseph Lakowicz, Henryk Szmacinski, Klaus Berndt

Proceedings Volume 1648, (1992) https://doi.org/10.1117/12.58296

KEYWORDS: Sensors, Modulation, Phase shift keying, Luminescence, Phase measurement, Phase modulation, Fiber optics, Fiber optics sensors, Modulators, Helium neon lasers

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Proceedings Article | 1 April 1992 Paper

Fluorescence lifetime imaging of Ca2+ using visible wavelength excitation and emission

Joseph Lakowicz, Henryk Szmacinski, Kazimierz Nowaczyk, Michael Johnson

Proceedings Volume 1640, (1992) https://doi.org/10.1117/12.58231

KEYWORDS: Phase shift keying, Modulation, Fluorescence lifetime imaging, Calcium, Luminescence, Sensors, Image intensifiers, Biochemistry, Laser spectroscopy, Microscopy

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Proceedings Article | 1 April 1992 Paper

Site-to-site diffusion in proteins as observed by energy transfer and frequency-domain fluorometry

Joseph Lakowicz, Ignacy Gryczynski, Jozef Kusba, Wieslaw Wiczk, Henryk Szmacinski, Michael Johnson

Proceedings Volume 1640, (1992) https://doi.org/10.1117/12.58215

KEYWORDS: Diffusion, Energy transfer, Proteins, Laser spectroscopy, Biochemistry, Molecules, Modulation, Luminescence, Phase shift keying, Chemical oxygen iodine lasers

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Proceedings Article | 1 April 1992 Paper

Detection of a distance-dependent rate of quenching by frequency-domain fluorometry

Jozef Kusba, Ignacy Gryczynski, Henryk Szmacinski, Michael Johnson, Joseph Lakowicz

Proceedings Volume 1640, (1992) https://doi.org/10.1117/12.58200

KEYWORDS: Data modeling, Diffusion, Luminescence, Laser spectroscopy, Biochemistry, Modulation, Phase shift keying, Biological research, Carbon, Optical simulations

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Proceedings Article | 1 July 1991 Paper

Frequency-domain fluorescence spectroscopy: instrumentation and applications to the biosciences

Joseph Lakowicz, Ignacy Gryczynski, Henryk Malak, Michael Johnson, Gabor Laczko, Wieslaw Wiczk, Henryk Szmacinski, Jozef Kusba

Proceedings Volume 1435, (1991) https://doi.org/10.1117/12.44239

KEYWORDS: Modulation, Picosecond phenomena, Diffusion, Fluorescence spectroscopy, Phase shift keying, Time metrology, Luminescence, Sensors, Microchannel plates, Light sources

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Proceedings Article | 1 May 1990 Paper

Deviation from the Forster theory for time-dependent donor decays for randomly distributed molecules in solution

Joseph Lakowicz, Henryk Szmacinski, Michael Johnson

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17747

KEYWORDS: Molecules, Energy transfer, Laser spectroscopy, Biochemistry, Absorption, Failure analysis, Medicine, Molecular interactions, Diffusion, Modulation

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Proceedings Article | 1 May 1990 Paper

Influence of end-to-end diffusion on intramolecular energy transfer as observed by frequency-domain fluorometry

Joseph Lakowicz, Wieslaw Wiczk, Ignacy Gryczynski, Henryk Szmacinski, Michael Johnson

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17748

KEYWORDS: Diffusion, Data modeling, Energy transfer, Biochemistry, Laser spectroscopy, Modulation, Molecules, Luminescence, Quantum efficiency, Phase shift keying

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Showing 5 of 25 publications

Conference Committee Involvement (2)

Advanced Biomedical and Clinical Diagnostic Systems

25 January 2004 | San Jose, CA, United States

Advanced Biomedical and Clinical Diagnostic Systems

26 January 2003 | San Jose, CA, United States

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