Dr. Weixing Cai Profile

Dr. Weixing Cai

Research Assistant Professor at Brigham and Women's Hospital

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Author

Publications (21)

Proceedings Article | 19 March 2014 Paper

Effect of coherence loss in differential phase contrast imaging

Weixing Cai, Ruola Ning, Jiangkun Liu

Proceedings Volume 9033, 903357 (2014) https://doi.org/10.1117/12.2043904

KEYWORDS: Coherence (optics), X-rays, Visibility, Image retrieval, Phase contrast, X-ray imaging, Skin, Tissues, Signal attenuation, Sensors

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Proceedings Article | 19 March 2013 Paper

Phantom study for volume-of-interest breast imaging using differential phase contrast cone beam CT (DPC-CBCT)

Jiangkun Liu, Ruola Ning, Weixing Cai

Proceedings Volume 8668, 866850 (2013) https://doi.org/10.1117/12.2007159

KEYWORDS: Imaging systems, Signal attenuation, Breast, Image filtering, Phase contrast, Breast imaging, X-rays, Linear filtering, Visualization, X-ray computed tomography

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Proceedings Article | 19 March 2013 Paper

Feasibility study of spectral imaging for differential phase contrast cone beam CT: computer simulations

Weixing Cai, Ruola Ning, Jiangkun Liu

Proceedings Volume 8668, 86684Z (2013) https://doi.org/10.1117/12.2007147

KEYWORDS: X-rays, X-ray imaging, Computer simulations, Image processing, Phase contrast, Sensors, Imaging spectroscopy, Image quality, Image enhancement, Phase shifts

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Proceedings Article | 9 March 2012 Paper

Investigation of Moiré pattern-based phase retrieval approach for differential phase-contrast cone beam CT imaging using a hospital-grade tube

Weixing Cai, Ruola Ning, Yang Yu, Jiangkun Liu, David Conover

Proceedings Volume 8313, 83132R (2012) https://doi.org/10.1117/12.911342

KEYWORDS: Phase retrieval, X-rays, Image retrieval, X-ray computed tomography, X-ray imaging, Spatial resolution, Fourier transforms, Sensors, Image quality, Spatial frequencies

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Proceedings Article | 9 March 2012 Paper

Performance investigation of a hospital-grade x-ray tube-based differential phase-contrast cone beam CT system

Yang Yu, Ruola Ning, Weixing Cai, Jiangkun Liu, David Conover

Proceedings Volume 8313, 83134F (2012) https://doi.org/10.1117/12.911400

KEYWORDS: X-rays, X-ray computed tomography, X-ray imaging, Phase contrast, Imaging systems, Sensors, Phase retrieval, Tissues, Picosecond phenomena, Absorption

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Proceedings Article | 9 March 2012 Paper

Investigation of source grating stepping for differential phase-contrast cone-beam CT (DPC-CBCT) system

Weixing Cai, Yang Yu, Ruola Ning, Jiangkun Liu, David Conover

Proceedings Volume 8313, 83132S (2012) https://doi.org/10.1117/12.911422

KEYWORDS: X-rays, Imaging systems, X-ray imaging, X-ray computed tomography, Phase shifts, Image quality, Phase contrast, Tolerancing, Diffraction gratings, Sensors

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Differential phase contrast (DPC) imaging, which utilizes phase shift information of X-ray, has the potential of dramatically increasing the contrast in biological sample imaging compared to attenuation-based method that relies on X-ray absorption information, since the X-ray phase is much more sensitive than the attenuation during transmission. In a DPC imaging system, the phase stepping method is widely used to obtain DPC images: at each angle the phase grating is shifted incrementally to produce a set of images and then the so obtained images are used to retrieve DPC image. However, DPC imaging requires a high mechanical precision to perform phase stepping, which is generally one order higher than the period of phase grating. Given that phase grating period is generally 2-4 um, the requirement of mechanical accuracy and stability are very demanding (<0.5um) and difficult to meet in a system with rotating gantry. In this paper, we present a method that is able to greatly relax the requirement of mechanical accuracy and stability by stepping the source grating rather than the analyzer grating. This method is able to increase the system's mechanical tolerance without compromising image quality and make it feasible to install the system on a rotating gantry to perform differential phase-contrast cone beam CT (DPC-CBCT). It is also able to increase the grating shifting precision and as a result improve the reconstructed image quality. Mechanical tolerance investigation and image quality investigation at different phase stepping schemes and different dose levels will be carried out on both the original modality and the new modality, the results will be evaluated and compared. We will deliberately create random mechanical errors in phase stepping and evaluate the resulting DPC images and DPC-CBCT reconstructions. The contrast, noise level and sharpness will be evaluated to assess the influence of mechanical errors. By stepping the source grating, the system is expected to tolerate an error of 6-7 times bigger than that with analyzer grating stepping.

Proceedings Article | 17 March 2011 Paper

Performance evaluation of a differential phase-contrast cone-beam (DPC-CBCT) system for soft tissue imaging

Yang Yu, Ruola Ning, Weixing Cai

Proceedings Volume 7961, 79614X (2011) https://doi.org/10.1117/12.878492

KEYWORDS: X-rays, Imaging systems, X-ray imaging, Tissues, X-ray computed tomography, Sensors, Reconstruction algorithms, X-ray detectors, Computed tomography, Phase contrast

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Proceedings Article | 23 March 2010 Paper

Design and construction of a micro-focus in-line phase-contrast cone-beam CT (PC-CBCT) system for soft tissue imaging

Weixing Cai, Ruola Ning

Proceedings Volume 7622, 76225F (2010) https://doi.org/10.1117/12.844379

KEYWORDS: X-rays, Imaging systems, Sensors, X-ray computed tomography, Tissues, X-ray imaging, Image enhancement, Tomography, Signal attenuation, X-ray detectors

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Proceedings Article | 23 March 2010 Paper

Pseudo super-resolution for improved calcification characterization for cone beam breast CT (CBBCT)

Jiangkun Liu, Ruola Ning, Weixing Cai

Proceedings Volume 7622, 762236 (2010) https://doi.org/10.1117/12.844353

KEYWORDS: Image quality, Modulation transfer functions, Sensors, Breast, X-rays, Image processing, Super resolution, X-ray imaging, Lawrencium, Visualization

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Proceedings Article | 14 March 2009 Paper

Dose efficiency consideration for volume-of-interest breast imaging using x-ray differential phase-contrast CT

Weixing Cai, Ruola Ning

Proceedings Volume 7258, 72584D (2009) https://doi.org/10.1117/12.813837

KEYWORDS: X-rays, Sensors, X-ray imaging, Breast, Breast imaging, Imaging systems, Reconstruction algorithms, Computer simulations, Phase shifts, X-ray detectors

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SPIE Journal Paper | 1 September 2008

Simplified method of scatter correction using a beam-stop-array algorithm for cone-beam computed tomography breast imaging

Weixing Cai, Ruola Ning, David Conover

OE, Vol. 47, Issue 09, 097003, (September 2008) https://doi.org/10.1117/12.10.1117/1.2977527

KEYWORDS: Breast, X-rays, Reconstruction algorithms, Breast imaging, Prototyping, Tumors, Scatter measurement, Sensors, X-ray imaging, Chest

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Proceedings Article | 19 March 2008 Paper

Development of a quality control program for a cone beam CT imaging system

Ricardo Betancourt Benítez, Ruola Ning, David Conover, Yan Zhang, Weixing Cai

Proceedings Volume 6913, 691356 (2008) https://doi.org/10.1117/12.770427

KEYWORDS: Imaging systems, Image quality, Modulation transfer functions, Computed tomography, X-ray computed tomography, Spatial resolution, Control systems, Sensors, Spatial frequencies, Image quality standards

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Proceedings Article | 18 March 2008 Paper

Cone-beam reconstruction using retrieved phase projections of in-line holography for breast imaging

Weixing Cai, Ruola Ning

Proceedings Volume 6913, 69132Q (2008) https://doi.org/10.1117/12.770727

KEYWORDS: Breast imaging, Holography, Imaging systems, X-rays, Tumors, Breast, Sensors, X-ray imaging, Holograms, Reconstruction algorithms

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SPIE Journal Paper | 1 March 2008

Preliminary study of a phase-contrast cone-beam computed tomography system: the edge-enhancement effect in the tomographic reconstruction of in-line holographic images

Weixing Cai, Ruola Ning

OE, Vol. 47, Issue 03, 037004, (March 2008) https://doi.org/10.1117/12.10.1117/1.2897284

KEYWORDS: Holography, Reconstruction algorithms, Signal attenuation, Holograms, Sensors, 3D image reconstruction, X-rays, Imaging systems, Optical engineering, Near field diffraction

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Proceedings Article | 15 March 2007 Paper

A novel cone beam breast CT scanner: system evaluation

Ruola Ning, David Conover, Yong Yu, Yan Zhang, Weixing Cai, Ricardo Betancourt-Benitez, Xianghua Lu

Proceedings Volume 6510, 651030 (2007) https://doi.org/10.1117/12.710340

KEYWORDS: Breast, X-ray computed tomography, Scanners, Mammography, Imaging systems, Tumors, Spatial resolution, X-rays, Sensors, Image quality

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Proceedings Article | 14 March 2007 Paper

Evaluation of a new breast-shaped compensation filter for a newly built breast imaging system

Weixing Cai, Ruola Ning, Yan Zhang, David Conover

Proceedings Volume 6510, 651039 (2007) https://doi.org/10.1117/12.710167

KEYWORDS: Breast, Chest, X-rays, Image filtering, Breast imaging, Imaging systems, Signal attenuation, Tumors, Aluminum, Image quality

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Proceedings Article | 2 March 2006 Paper

Flat panel detector-based cone beam CT for dynamic imaging: system evaluation

Ruola Ning, David Conover, Yong Yu, Yan Zhang, Weixing Cai, Dong Yang, Xianghua Lu

Proceedings Volume 6142, 61422C (2006) https://doi.org/10.1117/12.655717

KEYWORDS: Prototyping, Sensors, Imaging systems, X-rays, X-ray computed tomography, Chest, X-ray detectors, Breast, Data acquisition, X-ray imaging

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Proceedings Article | 2 March 2006 Paper

Computer simulation of FDK reconstruction with the in-line holographic projection data

Weixing Cai, Ruola Ning, Dong Yang

Proceedings Volume 6142, 61424G (2006) https://doi.org/10.1117/12.655606

KEYWORDS: Signal attenuation, Holography, X-rays, Sensors, Reconstruction algorithms, 3D image reconstruction, Computer simulations, X-ray sources, Phase contrast, Detection and tracking algorithms

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Proceedings Article | 2 March 2006 Paper

Scatter correction using beam stop array algorithm for cone-beam CT breast imaging

Weixing Cai, Ruola Ning, David Conover

Proceedings Volume 6142, 61423E (2006) https://doi.org/10.1117/12.655587

KEYWORDS: Breast, Reconstruction algorithms, Detection and tracking algorithms, Sensors, Breast imaging, Chest, Tumors, Prototyping, X-rays, Computed tomography

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Proceedings Article | 2 March 2006 Paper

A novel cone beam breast CT scanner: preliminary system evaluation

Ruola Ning, David Conover, Yong Yu, Yan Zhang, Weixing Cai, Xianghua Lu, Richardo Betancourt-Benitez

Proceedings Volume 6142, 614211 (2006) https://doi.org/10.1117/12.655741

KEYWORDS: Breast, Scanners, Computed tomography, Mammography, Prototyping, Sensors, CT reconstruction, X-ray computed tomography, Tumors, Breast imaging

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Proceedings Article | 20 April 2005 Paper

Flat panel detector-based cone beam CT lung imaging: preliminary system evaluation

Ruola Ning, David Conover, Yong Yu, Weixing Cai, Xianghua Lu

Proceedings Volume 5745, (2005) https://doi.org/10.1117/12.596114

KEYWORDS: X-ray computed tomography, Sensors, Prototyping, Imaging systems, Data acquisition, Scanners, X-rays, Tumors, Spatial resolution, Computed tomography

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Showing 5 of 21 publications

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