Prof. Wen Xiao Profile

Prof. Wen Xiao

at BeiHang Univ

SPIE Involvement:

Author

Publications (30)

Proceedings Article | 30 April 2024 Paper

Detecting intracellular onion-like carbon nanostructures based on cell biolens’ properties by holographic flow cytometry

Yijing Li, Yakun Liu, Yuchen Feng, Qi Zhao, Xi Xiao, Hao Wang, Wen Xiao, Feng Pan

Proceedings Volume 13157, 1315705 (2024) https://doi.org/10.1117/12.3013239

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Proceedings Article | 11 August 2023 Poster + Paper

Three-dimensional distribution dynamic change observation of carbon nano-onions particle inside cancer cell based on digital holographic tomography

Yakun Liu, Wen Xiao, Xiaosu Yi, Xi Xiao, Hao Wang, Ran Peng, Yuchen Feng, Qi Zhao, Feng Pan

Proceedings Volume 12622, 126221B (2023) https://doi.org/10.1117/12.2676365

KEYWORDS: Cancer, Nanoparticles

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Proceedings Article | 11 August 2023 Presentation + Paper

Classification of drug-resistant ovarian cancer cells using holographic flow cytometry through interpretable machine learning

Lu Xin, Wen Xiao, Huanzhi Zhang, Xiaosu Yi, Xiao ping Li, Feng Pan

Proceedings Volume 12622, 126220X (2023) https://doi.org/10.1117/12.2676101

KEYWORDS: Cancer, Machine learning, Resistance, Ovarian cancer, Holography, Digital holography, Holographic interferometry, Chemotherapy, Flow cytometry, 3D image reconstruction

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Proceedings Article | 11 August 2023 Presentation + Paper

High-throughput and high-precision flow cytometry based on digital holographic microscopy

Feng Pan, Wen Xiao, Lu Xin, Hao Wang, Ran Peng, Xi Xiao

Proceedings Volume 12622, 126220B (2023) https://doi.org/10.1117/12.2674497

KEYWORDS: Quantitative biology, Optical biology, Cancer, Digital holography, Holography, Flow cytometry, Cancer detection, Microscopy, Deep learning, Machine learning

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Proceedings Article | 20 June 2021 Presentation + Paper

Rapid autofocusing for dynamic observation exploiting holographic polarization microscope

Leiping Che, Wen Xiao, Pietro Ferraro, Feng Pan

Proceedings Volume 11786, 117860P (2021) https://doi.org/10.1117/12.2592794

KEYWORDS: Polarization, Microscopes, Holography, Image restoration, Multiplexing, Image segmentation, Wave propagation, Tissue optics, Reconstruction algorithms, Photography

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Proceedings Article | 20 June 2021 Presentation + Paper

Automatic compensation of phase aberration in digital holographic microscopy with deep neural networks for monitoring the morphological response of bone cells under fluid shear stress

Lu Xin, Wen Xiao, Runyu Cao, Xintong Wu, Pietro Ferraro, Feng Pan

Proceedings Volume 11786, 117860O (2021) https://doi.org/10.1117/12.2592793

KEYWORDS: Digital holography, Bone, Microfluidics, Microscopy, Holography, Tissues, Neural networks, Fluid dynamics, Reconstruction algorithms, Microfluidic imaging

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In bone tissue, osteocytes are embedded within a microfluid-filled network which expose them to high levels of fluid shear stress (FSS). The osteocytes’ sensitivity to different levels of FSS has demonstrated. However, there are few attempts to image 3D cellular deformation under FSS by label-free and quantitative microscopy. Digital holographic (DH) microscopy is a powerful imaging technique that can provide rich intracellular information based on the refractive index (RI) contrast, without exogenous contrast agents. However, in DH image recording process, the recorded wave-front contains not only the object’s information but also the aberrations caused by the microscope objective (MO) and the imperfections of optical components of the system. The fitting-based numerical method removes total aberrations by detecting object-free background as reference surfaces. In this paper, we proposed a convolutional neural network (CNN) for multivariate regression to cope with the phase aberration compensation problem automatically thus allows performing long-term monitoring of bone cells morphological response under FSS. We transformed the problem of estimating the coefficients for fitting a phase aberration map to a regression problem. The aberrated phase images are put into this model which can automatically learns the internal features of phase aberrations. Then the optimal coefficients are estimated as an output of the network. Based on these coefficients, the phase aberration map is built by the polynomial fitting, and the phase aberrations are removed by subtracting the aberration phase image with the phase map. The trainning and validation set contain thousands of phase image of cells. The mean square error (MSE) is used as the loss function. Then, the trained model was used for aberrations compensation in the FFS experiment of osteocytes. The results show that the proposed approach can predict the optimal coefficients and automatically compensating the phase aberrations without detecting background regions and knowing any physical parameters.

Proceedings Article | 4 March 2019 Paper

Drug resistance detection of endometrial cancer cell lines using digital holographic microscopy

Runyu Cao, Wen Xiao, Xiaosu Yi, Feng Pan, Tian Yao, Xiaoping Li

Proceedings Volume 10887, 1088721 (2019) https://doi.org/10.1117/12.2510821

KEYWORDS: Cancer, Digital holography, Holography, Microscopy, Phase imaging

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Proceedings Article | 6 November 2018 Paper

Remote sensing image classification method based on active-learning deep neural network

Wen Xiao, Junqiu Zou, Kuan Xu

Proceedings Volume 10817, 108171G (2018) https://doi.org/10.1117/12.2504455

KEYWORDS: Remote sensing, Image classification, Neural networks, Convolutional neural networks, Evolutionary algorithms, Detection and tracking algorithms, Machine learning, Hyperspectral imaging, Statistical modeling, Data processing

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Proceedings Article | 18 August 2018 Paper

High-accuracy three-dimensional tomographic observation of cell clusters

Ying Li, Feng Pan, Xichao Ma, Wen Xiao, Xiaosu Yi

Proceedings Volume 10749, 107491D (2018) https://doi.org/10.1117/12.2324967

KEYWORDS: Tomography, Capillaries, Reconstruction algorithms, Digital holography, Liquids, Holograms, Ovarian cancer, Holography, Refractive index

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Proceedings Article | 18 August 2018 Presentation + Paper

Unlabeled flow cellular deformation measurement based on digital holographic microscopy

Wen Xiao, Qixiang Wang, Feng Pan, Runyu Cao, Xiaosu Yi

Proceedings Volume 10749, 107490L (2018) https://doi.org/10.1117/12.2324852

KEYWORDS: Digital holography, Holography, Holograms, Microscopy, Bone, Beam splitters, Fluid dynamics, Digital filtering, Optical filters, Refractive index

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Proceedings Article | 12 January 2018 Paper

Real-time micro-vibration multi-spot synchronous measurement within a region based on heterodyne interference

Ma Lan, Wen Xiao, Zonghui Chen, Hongliang Hao, Feng Pan

Proceedings Volume 10621, 1062118 (2018) https://doi.org/10.1117/12.2292664

KEYWORDS: Detection and tracking algorithms, Heterodyning, Demodulation, Velocity measurements, Cameras, High speed imaging, Optical testing, Interferometry, Image acquisition, Image processing

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Proceedings Article | 10 January 2018 Paper

A method of noise reduction in heterodyne interferometric vibration metrology by combining auto-correlation analysis and spectral filtering

Hongliang Hao, Wen Xiao, Zonghui Chen, Lan Ma, Feng Pan

Proceedings Volume 10616, 106161D (2018) https://doi.org/10.1117/12.2295331

KEYWORDS: Heterodyning, Demodulation, Interferometry, Denoising, Metrology

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Proceedings Article | 24 October 2017 Paper

Image quality improvement in optical diffraction tomography by multiple numerical propagations and separated reconstructions

Xichao Ma, Wen Xiao, Feng Pan

Proceedings Volume 10462, 104622C (2017) https://doi.org/10.1117/12.2284457

KEYWORDS: Tomography, Image quality, Optical tomography, Image processing, Digital holography

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Proceedings Article | 24 October 2017 Paper

Target interpretation of visible light image and infrared image fusion method

Wei Sun, Wen Xiao, Feng Pan, Chao Du

Proceedings Volume 10462, 104620E (2017) https://doi.org/10.1117/12.2282251

KEYWORDS: Image fusion, Visible radiation, Infrared imaging, Infrared radiation, Wavelet transforms

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Proceedings Article | 6 April 2017 Presentation + Paper

Digital holographic microtomography of fusion spliced optical fibers

Yating Deng, Wen Xiao, Xichao Ma, Feng Pan

Proceedings Volume 10127, 1012705 (2017) https://doi.org/10.1117/12.2250764

KEYWORDS: Digital holography, Fusion splicing, Optical fibers, 3D image processing, Holography, 3D metrology, Single mode fibers, Holograms, Polarization maintaining fibers, Digital recording, Reconstruction algorithms, Interfaces, Cladding

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Proceedings Article | 8 March 2017 Paper

Coherent noise reduction in digital holographic interferometry by slightly rotating object

Zheng Zhong, Wen Xiao, Feng Pan, Leiping Che

Proceedings Volume 10255, 1025543 (2017) https://doi.org/10.1117/12.2268135

KEYWORDS: Digital holography, Denoising, Holographic interferometry, Speckle, 3D image reconstruction, Holograms, Digital filtering, Optical filters, Electronic filtering, Gaussian filters

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SPIE Journal Paper | 3 March 2017

Automatic focus determination through cosine and modified cosine score in digital holography

Aga He, Wen Xiao, Feng Pan

OE, Vol. 56, Issue 03, 034103, (March 2017) https://doi.org/10.1117/12.10.1117/1.OE.56.3.034103

KEYWORDS: Digital holography, Holograms, Linear filtering, 3D image reconstruction, Optical engineering, Diffraction, Holography, Reconstruction algorithms, Image filtering, Optical simulations

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Proceedings Article | 10 February 2017 Paper

Surface quality inspection of laser gyro mirrors using digital holographic microscopy

Lizi Yang, Feng Pan, Wen Xiao, Runyu Cao

Proceedings Volume 10250, 102501O (2017) https://doi.org/10.1117/12.2267106

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Proceedings Article | 10 February 2017 Paper

Synchronous high speed multi-point velocity profile measurement by heterodyne interferometry

Xueqin Hou, Wen Xiao, Zonghui Chen, Xiaodong Qin, Feng Pan

Proceedings Volume 10250, 102500N (2017) https://doi.org/10.1117/12.2267051

KEYWORDS: Velocity measurements, Heterodyning, Interferometry, High speed imaging, CMOS cameras, Demodulation

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Proceedings Article | 10 February 2017 Paper

Micro-vibration detection with heterodyne holography based on time-averaged method

XiaoDong Qin, Feng Pan, ZongHui Chen, XueQin Hou, Wen Xiao

Proceedings Volume 10250, 1025032 (2017) https://doi.org/10.1117/12.2266922

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Proceedings Article | 31 October 2016 Paper

Autofocusing through cosine and modified cosine score in digital holography

Aga He, Wen Xiao, Feng Pan

Proceedings Volume 10022, 100222H (2016) https://doi.org/10.1117/12.2248502

KEYWORDS: Digital holography, Reconstruction algorithms, 3D image reconstruction, Optical simulations, Holography, Holograms, Diffraction, Optical imaging, Imaging systems, Algorithm development

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Proceedings Article | 22 August 2015 Paper

A low cost design to eliminate polarization induced phase shift for dual Mach-Zehnder fiber interferometer

Rui Li, Sheng Liang, Qianzhe Liu, Wen Xiao

Proceedings Volume 9656, 965609 (2015) https://doi.org/10.1117/12.2197578

KEYWORDS: Signal detection, Polarization, Phase shifts, Polarization control, Control systems, Mach-Zehnder interferometers, Ceramics, Interferometers, Polarizers, Sensors

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Proceedings Article | 20 August 2013 Paper

Distortion correction on numerical reconstruction of digital holography on arbitrarily tilted recording planes

Juan Wang, Wen Xiao, Feng Pan, Chuan Gao

Proceedings Volume 8913, 89130V (2013) https://doi.org/10.1117/12.2034542

KEYWORDS: Digital holography, Holograms, Distortion, Diffraction, 3D image reconstruction, Holography, Beam splitters, Image quality, Fourier transforms, Computer generated holography

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Proceedings Article | 13 October 2008 Paper

A theoretical analysis on parameters of fiber optic displacement sensor

Bingshi Xu, Wen Xiao, Dong Yao

Proceedings Volume 7129, 71290P (2008) https://doi.org/10.1117/12.807636

KEYWORDS: Fiber optics sensors, Sensors, Reflectors, Fiber optics, Modulation, Mathematical modeling, Mirrors, Optoelectronics, Sensor performance, Performance modeling

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Proceedings Article | 13 October 2008 Paper

Optical fiber Fabry-Perot cavity applied to an optical microphone

Junlei Chang, Wen Xiao

Proceedings Volume 7129, 71290I (2008) https://doi.org/10.1117/12.807627

KEYWORDS: Optical fibers, Mathematical modeling, Fabry–Perot interferometers, Reflectivity, Visibility, Information operations, Semiconductors, Optoelectronics, Sensors, Structural design

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Proceedings Article | 22 February 2008 Paper

Design of a night vision system with laser illumination based on DSP

Yang Liu, Wen Xiao, Haiyang Wang

Proceedings Volume 6622, 66221M (2008) https://doi.org/10.1117/12.790905

KEYWORDS: Digital signal processing, Image processing, Imaging systems, Detection and tracking algorithms, Night vision systems, Semiconductor lasers, Signal processing, Infrared imaging, Image quality, Digital filtering

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Proceedings Article | 29 January 2007 Paper

Fiber micro-vibration readout sensor based on MOEMS

Rui Li, Wen Xiao, Dewen Liu, Yu Cui

Proceedings Volume 6279, 627964 (2007) https://doi.org/10.1117/12.725507

KEYWORDS: Fiber optics sensors, Sensors, Structured optical fibers, Microopto electromechanical systems, Reflectivity, Ceramics, Modulation, Ferroelectric materials, Signal detection, Fiber optics tests

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Proceedings Article | 28 October 2006 Paper

Research on two light sources design in fiber optic gyroscope for space application

Dewen Liu, Wen Xiao, Yanling Han

Proceedings Volume 6358, 63581Q (2006) https://doi.org/10.1117/12.717843

KEYWORDS: Fiber optic gyroscopes, Gyroscopes, Reliability, Radiation effects, Astronomical imaging, Light sources, Optical design, Phase modulation, Fiber optics, Satellites

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Proceedings Article | 19 May 2006 Paper

Micro-structured optic fiber system for pressure sensing

Xiaosu Yi, Wen Xiao, Rie Li

Proceedings Volume 6150, 61500W (2006) https://doi.org/10.1117/12.676742

KEYWORDS: Structured optical fibers, Modulation, Fiber optics sensors, Reflection, Sensors, Sensing systems, Optical fibers, Interference (communication), Acoustics, Physics

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Proceedings Article | 5 January 2006 Paper

Research on the key techniques of fiber optic gyroscopes in space applications

Wen Xiao, Dewen Liu, Yuyan Zhang

Proceedings Volume 5985, 59855O (2006) https://doi.org/10.1117/12.658646

KEYWORDS: Fiber optic gyroscopes, Gyroscopes, Reliability, Phase modulation, Fiber lasers, Astronomical imaging, Satellites, Structured optical fibers, Optics manufacturing, Fiber optics

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Showing 5 of 30 publications

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