Dr. Yaobing Chen Profile

Dr. Yaobing Chen

at Huazhong Univ of Science and Technology

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 15 February 2021 Poster + Presentation + Paper

Multiple-datasets and multiple-label based color normalization in histopathology with cGAN

Jing Ke, Yiqing Shen, Xinyu Jiang, Yi Guo, Yaobing Chen, Xiaoyao Liang

Proceedings Volume 11603, 1160310 (2021) https://doi.org/10.1117/12.2580688

KEYWORDS: Cancer, Tissues, Pathology, Data centers, Convolutional neural networks, Associative arrays

Read Abstract +

Computational histopathology algorithms can interpret very large volumes of data, which can navigate pathologists to assess slides promptly, and also aid in the localization and quantification of abnormal cells or tissues. In recent years, taking place of conventional imaging processing methods, deep learning has become the mainstream methodology to interpret cancer pathology images. However, similar as conventional computer vision methods, stain normalization in tissue identification with convolutional neural networks (CNNs) is still essential for the diagnostic accuracy. Traditional prior knowledge-oriented color matching, as well as a particular style based pure learning in generative adversarial networks, may be encompassed with accuracy decrease when data centers are many. In this paper, we propose a novel color normalization method with a conditional generative adversarial network (cGAN). It is a learning-based interpolation approach with probability distribution space on multiple datasets training. A target template is designed to be label-dependent to overcome the improper color mapping problem caused by data heterogeneity. The tests are performed on histopathology datasets from The Cancer Genome Atlas (TCGA) and the proposed method outperforms other previous works in classification accuracy. This approach has potential in clinical practice for better recognition of cancer in digital pathology and can be implemented in a decentralized setting.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years