Diffusing Wave Spectroscopy (DWS) employs non-invasive techniques to study dynamic behaviors within scattering mediums. This involves detecting speckle light patterns from the moving media and gauging speckle decorrelation time for dynamic quantification. A specific form of DWS is Speckle Visibility Spectroscopy (SVS), which employs spatial ensembles by utilizing a high-pixel-count cameras to capture multiple speckles in a single frame. To further increase SNR at low signal level, one combines interferometric techniques with SVS to form interferometric SVS (iSVS).
In this talk, I will present the benefits and constraints associated with the utilization of interferometric detection (iSVS) over direct detection (SVS). Surprisingly, we found that iSVS does not always outperform SVS, but it does emerge as the prevailing choice in most cases.
Measuring blood flow on the head is an indirect yet crucial way to access or quantify brain activity non-invasively, useful for diagnosing traumatic brain injuries by looking at the changes of blood flow. However, measuring the cerebral blood flow (CBF) remains challenging, principally due to the ability to reach and collect signal from the brain. In this talk, I will present our efforts in building an affordable, compact, and portable laser device for real-time Cerebral Blood Flow (CBF) monitoring. Our technique draws upon the speckle visibility spectroscopy technique, using the spatial ensemble of the speckle field to evaluate blood flow dynamics.
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