Dr. Yukio Ueda
Deputy Director at Hamamatsu Photonics K.K.
SPIE Involvement:
Author
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Profile Summary

Duties
He has been in charge of everything from manufacturing to development, new business planning, sales, etc. at a major medical device manufacturer, and currently oversees research in the biomedical field using light at the central research laboratory of a major optical device manufacturer. In the life science field, biophotonic measurement technology that enables non-contact, non-invasive, and unconscious measurement is highly anticipated, and since he has been involved in various R&D projects, he has accumulated expertise in this field (such as brain function measurement using light, cancer diagnosis, and blood glucose level measurement). Based on these achievements, in parallel with his current position, he also serves as an extramural lecturer at Kyoto University Graduate School, a part-time lecturer at the University of Tokyo Graduate School, and a director of a special-purpose subsidiary.

Studies
He has been developing a time-resolved diffuse optical tomography (DOT) imaging system involving multi-channel time-resolved spectroscopy. It is highly anticipated that DOT will make it possible to capture images of breast tumors and brain activity in three-dimensions by means of near-infrared light. The use of DOT especially for breast cancer diagnosis, so-called optical mammography, is not expected to provide precise anatomical information; however, it could provide evidence of angiogenesis, metabolic activity and oxygen consumption in the tumor. His system uses the time-correlated single photon counting method. The detector modules and the signal processing circuits were custom-made to obtain a high signal to noise ratio, and high temperature stability with a high temporal resolution. The system had excellent reproducibility in three dimensions and enabled comparison of the total hemoglobin concentration images of the breast during chemotherapy. Therefore, his system also has the potential to evaluate the effectiveness of chemotherapy.
Publications (11)

Proceedings Article | 7 March 2023 Poster + Paper
Kenji Yoshimoto, Hiroko Wada, Etsuko Ohmae, Nobuko Yoshizawa, Kei Koizumi, Hiroyuki Ogura, Hiroaki Suzuki, Shu Homma, Tetsuya Mimura, Norihiro Suzuki, Hatsuko Nasu, Yuko Asano, Satoshi Goshima, Yukio Ueda
Proceedings Volume 12376, 123760R (2023) https://doi.org/10.1117/12.2652140
KEYWORDS: Breast cancer, Medical image reconstruction, Mammography, Diffuse optical tomography, Ultrasonography

SPIE Journal Paper | 13 October 2022 Open Access
Hiroko Wada, Nobuko Yoshizawa, Etsuko Ohmae, Yukio Ueda, Kenji Yoshimoto, Tetsuya Mimura, Hatsuko Nasu, Yuko Asano, Hiroyuki Ogura, Harumi Sakahara, Satoshi Goshima
JBO, Vol. 27, Issue 10, 105002, (October 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.10.105002
KEYWORDS: Breast, Tissues, Chest, Tissue optics, Mammary gland, Breast cancer, Reflectivity, Photonics, Diffuse optical spectroscopy, Mammography

Proceedings Article | 9 March 2021 Poster + Paper
Kenji Yoshimoto, Hiroko Wada, Nobuko Yoshizawa, Hiroyuki Ogura, Etsuko Ohmae, Hiroaki Suzuki, Shu Homma, Tetsuya Mimura, Norihiro Suzuki, Yuko Asano, Satoshi Goshima, Yukio Ueda
Proceedings Volume 11639, 116391I (2021) https://doi.org/10.1117/12.2576597
KEYWORDS: Reflectivity, Breast cancer, Diffuse optical tomography, Optical imaging, Mammography, Diffuse optical imaging, Tumors, Tissues, Breast, Oxygen

Proceedings Article | 1 March 2019 Presentation + Paper
Hiroaki Suzuki, Etsuko Ohmae, Kenji Yoshimoto, Hiroko Wada, Shu Homma, Norihiro Suzuki, Tetsuya Mimura, Yutaka Yamashita, Yukio Ueda
Proceedings Volume 10874, 108740A (2019) https://doi.org/10.1117/12.2507429
KEYWORDS: Tissues, Abdomen, Near infrared spectroscopy, Optical fibers, Scattering, Gallium arsenide, Indium gallium arsenide, Oxygen

SPIE Journal Paper | 27 February 2018 Open Access
Nobuko Yoshizawa, Yukio Ueda, Tetsuya Mimura, Etsuko Ohmae, Kenji Yoshimoto, Hiroko Wada, Hiroyuki Ogura, Harumi Sakahara
JBO, Vol. 23, Issue 02, 026010, (February 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.2.026010
KEYWORDS: Tumors, Breast, Tissues, Breast cancer, Tissue optics, Optical testing, Chest, Scattering, Absorption, Near infrared spectroscopy

Showing 5 of 11 publications
Conference Committee Involvement (3)
Optical Tomography and Spectroscopy of Tissue XVI
25 January 2025 | San Francisco, California, United States
Optical Tomography and Spectroscopy of Tissue XV
30 January 2023 | San Francisco, California, United States
Optical Tomography and Spectroscopy of Tissue XIV
6 March 2021 | Online Only, California, United States
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