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22 July 2019 Single blood cell Raman spectroscopy reveals elevated haemoglobin content in poikilocytosis
Suet Man Tsui, Condon Lau
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Proceedings Volume 11075, Novel Biophotonics Techniques and Applications V; 110751A (2019) https://doi.org/10.1117/12.2526740
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany
Abstract
In this study, confocal Raman spectroscopy revealed biochemical differences between single normal red blood cells and poikilocytes. The intensities of 5 Raman bands associated with oxygenated RBCs are larger in acanthocytes than normal and normal-looking RBCs. Overall, acanthocytes carry more haemoglobin and this is corroborated by CBC and ICP-MS.
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Suet Man Tsui and Condon Lau "Single blood cell Raman spectroscopy reveals elevated haemoglobin content in poikilocytosis", Proc. SPIE 11075, Novel Biophotonics Techniques and Applications V, 110751A (22 July 2019); https://doi.org/10.1117/12.2526740
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KEYWORDS
Blood
Raman spectroscopy
Control systems
Titanium
Statistical analysis
Confocal microscopy
Iron
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