Development of a thermoacoustic imaging system to image blood in the brain: preliminary ex vivo results

Md Tarikul Islam; Juliana Benavides; Ravi Prakash; Laura McGuire; Fady Charbel; James Lin; Danilo Erricolo; Juri Gelovani; Kamran Avanaki

doi:10.1117/12.3003489

12 March 2024 Development of a thermoacoustic imaging system to image blood in the brain: preliminary ex vivo results

Md Tarikul Islam, Juliana Benavides, Ravi Prakash, Laura McGuire, Fady Charbel, James Lin, Danilo Erricolo, Juri Gelovani, Kamran Avanaki

Author Affiliations +

Proceedings Volume 12842, Photons Plus Ultrasound: Imaging and Sensing 2024; 128420S (2024) https://doi.org/10.1117/12.3003489
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Thermoacoustic imaging (TAI) is a promising new technology for biomedical diagnostics. It combines the high contrast of electromagnetic absorption with the high resolution of ultrasound imaging. Traditional TAI systems use circular scanning modes with single or arc detectors, which can be slow and inefficient for body scanning. A linear-array detector, which is commonly used in medical ultrasound imaging systems, can be used to scan biological tissues more efficiently. In this study, we developed a novel linear-array TAI system (LATIS) for the detection of hemorrhage in the brain through fontanelle in neonates. The LATIS uses a linear-array transducer with multiple elements, which enables rapid data acquisition and real-time imaging. A custom-designed trigger mechanism synchronizes the microwave signal generation and data acquisition process, ensuring accurate timing for optimal image quality. We evaluated the LATIS performance by conducting several ex-vivo sheep brain hemorrhage of different amounts of artificially induced blood. The system was able to successfully detect lower grades of intraventricular hemorrhages in ex-vivo experiments. These results demonstrate the potential of LATIS for clinical imaging of brain hemorrhage in neonates as they are vulnerable to intraventricular hemorrhage.

Citation Download Citation

Md Tarikul Islam, Juliana Benavides, Ravi Prakash, Laura McGuire, Fady Charbel, James Lin, Danilo Erricolo, Juri Gelovani, and Kamran Avanaki "Development of a thermoacoustic imaging system to image blood in the brain: preliminary ex vivo results", Proc. SPIE 12842, Photons Plus Ultrasound: Imaging and Sensing 2024, 128420S (12 March 2024); https://doi.org/10.1117/12.3003489

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available