Finite difference time-domain model of light scattering from retinal photoreceptors

Samer Abdallah; Alex Iolov; Omar M. Ramahi; Kostadinka Bizheva

doi:10.1117/12.763647

22 February 2008 Finite difference time-domain model of light scattering from retinal photoreceptors

Samer Abdallah, Alex Iolov, Omar M. Ramahi, Kostadinka Bizheva

Proceedings Volume 6864, Biomedical Applications of Light Scattering II; 68640H (2008) https://doi.org/10.1117/12.763647
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Functional ultra high resolution optical coherence tomography (fUHROCT) was used to non-invasively probe the functional response of retinal photoreceptors. Using this technique, time dependent changes in light reflectivity of the retinal photoreceptor layer were measured after external white light stimulation. The causes of the observed changes are currently not known. To better understand the observed reflectivity signals, we have developed a computational model based on the Finite-Difference Time-Domain method to simulate light scattering from retinal neurons. Preliminary simulation results suggest that cell dynamics and cell volume changes are the likely causes of the observed signals.

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Samer Abdallah, Alex Iolov, Omar M. Ramahi, and Kostadinka Bizheva "Finite difference time-domain model of light scattering from retinal photoreceptors", Proc. SPIE 6864, Biomedical Applications of Light Scattering II, 68640H (22 February 2008); https://doi.org/10.1117/12.763647

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KEYWORDS

Light scattering

Finite-difference time-domain method

Refractive index

Signal detection

Reflectivity

Retina

Scattering

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