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17 March 2023 Luminescent Gold nanoclusters for biosensing and bioimaging of extracellular vesicles (Conference Presentation)
Valerie Marchi, Régina Cheichio, Solène Ducarre, Celia Ravel, Maria Jose Lo Faro, Pascale Even-Hernandez
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Proceedings Volume PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII; PC1239501 (2023) https://doi.org/10.1117/12.2656666
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
According to their high electron density and ultrasmall size, gold nanoclusters (AuNCs) have unique luminescence and photoelectrochemical properties that make them very attractive for various biomedical fields. We present an overview of the interaction between ultrasmall luminescent gold nanoclusters and lipidic membranes through electrostatic attraction, showing that it is possible to induce a large change in membrane structures or not. An efficient method was developed to encapsulate them into vesicle for drug delivery. These probes are easily internalized into cells through specific membrane protein targeting and also in vivo organisms.
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Valerie Marchi, Régina Cheichio, Solène Ducarre, Celia Ravel, Maria Jose Lo Faro, and Pascale Even-Hernandez "Luminescent Gold nanoclusters for biosensing and bioimaging of extracellular vesicles (Conference Presentation)", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC1239501 (17 March 2023); https://doi.org/10.1117/12.2656666
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KEYWORDS
Biosensing
Gold
Luminescence
Adsorption
Microfluidics
Nanoparticles
Optical microscopy
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