Mr. Alexander Ho Profile

Alexander Ho

at Univ of Illinois

SPIE Involvement:

Author | Student Chapter Treasurer

Publications (10)

Proceedings Article | 13 March 2024 Presentation

Early selection of desired biopharmaceutical CHO cell lines using label-free multimodal optical microscopy and machine learning

Jindou Shi, Alexander Ho, Eric Chaney, Janet Sorrells, Kevin Tan, Aneesh Alex, Remben Talaban, Darold Spillman, Marina Marjanovic, Minh Doan, Steve Hood, Stephen Boppart

Proceedings Volume PC12846, PC1284603 (2024) https://doi.org/10.1117/12.3001298

KEYWORDS: Optical microscopy, Machine learning, Multiphoton fluorescence microscopy, Fluorescence lifetime imaging, Profiling, Ovary, Multiphoton microscopy, Multimodal imaging, Monte Carlo methods, Manufacturing

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Proceedings Article | 13 March 2024 Presentation

Probing magnetic field effects on cellular redox state using autofluorescence intensity and lifetime microscopy

Kevin Tan, Carlos Renteria, Rishyashring Iyer, Alexander Ho, Janet Sorrells, Robert Usselman, Stephen Boppart

Proceedings Volume PC12863, PC1286306 (2024) https://doi.org/10.1117/12.3003226

KEYWORDS: Magnetism, Autofluorescence, Imaging systems, Microscopy, Modulation, Quantum fields, Quantum effects, Biological imaging, Visualization, Tissues

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Proceedings Article | 13 March 2024 Presentation

Prognostic value of optical coherence tomography (OCT) with machine learning for assessing clinical outcomes of otitis media

Alexander Ho, Qian Jiang, Katherine Peterson, Roxanne Link, Guillermo Monroy, Darold Spillman, Edita Aksamitiene, Joseph Kerschner, Stephen Boppart, Minh Do

Proceedings Volume PC12818, (2024) https://doi.org/10.1117/12.3003143

KEYWORDS: Optical coherence tomography, Machine learning, Biofilms, Visual process modeling, Tissues, Diseases and disorders, Visualization, Video, Scattering, Image resolution

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Proceedings Article | 13 March 2024 Presentation

Predicting productivity in CHO cells based on co-occurrence of metabolism-related features in simultaneous label-free autofluorescence multiharmonic (SLAM) microscopy

Alexander Ho, Jindou Shi, Eric Chaney, Janet Sorrells, Kevin Tan, Aneesh Alex, Remben Talaban, Darold Spillman, Marina Marjanovic, Minh Doan, Steve Hood, Stephen Boppart

Proceedings Volume PC12854, PC1285407 (2024) https://doi.org/10.1117/12.3003094

KEYWORDS: Microscopy, Fluorescence lifetime imaging, Autofluorescence, Feature extraction, Support vector machines, Second harmonic generation, Proteins, Ovary, Multimodal imaging, Monte Carlo methods

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Proceedings Article | 13 March 2024 Poster

Self-supervised deep learning enables robust fluorescence lifetime estimation with limited photons

Jindou Shi, Alexander Ho, Kevin Tan, Janet Sorrells, Rishyashring Iyer, Eric Chaney, Darold Spillman, Marina Marjanovic, Stephen Boppart

Proceedings Volume PC12857, PC1285719 (2024) https://doi.org/10.1117/12.3001312

KEYWORDS: Fluorescence lifetime imaging, Photons, Fluorescence, Deep learning, Statistical analysis, Education and training, Biological research, Reliability, Molecular interactions, Microscopy

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Proceedings Article | 17 March 2023 Presentation

Imaging and assessment of human ear wax with optical coherence tomography

Alexander Ho, Guillermo Monroy, Edita Aksamitiene, Darold Spillman, Marina Marjanovic, Stephen Boppart

Proceedings Volume 12354, 1235402 (2023) https://doi.org/10.1117/12.2649235

KEYWORDS: Optical coherence tomography, Ear, Image segmentation, Signal attenuation, Proteins, Product engineering, Medicine, Imaging systems, Human subjects, Fungi

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Proceedings Article | 17 March 2023 Presentation

Integrated Raman spectroscopy and optical coherence tomography system for characterizing otitis media

Guillermo Monroy, Sean Fitzgerald, Andrea Locke, Jungeun Won, Darold Spillman, Alexander Ho, Farzana Zaki, Honggu Choi, Eric Chaney, Jay Werkhaven, Kevin Mason, Anita Mahadevan-Jansen, Stephen Boppart

Proceedings Volume 12354, 1235404 (2023) https://doi.org/10.1117/12.2648504

KEYWORDS: Optical coherence tomography, Ear, Raman spectroscopy, Remote sensing, Visualization, Prototyping, In vitro testing, Human subjects, Diagnostics, Bone

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Proceedings Article | 17 March 2023 Presentation

Microplasma exposure as a novel therapeutic treatment for otitis media demonstrated in a pre-clinical chinchilla model

Guillermo Monroy, Jinhong Kim, Alexander Ho, Andrey Mironov, Farzana Zaki, Darold Spillman, Gabrielle Choo-Kang, Jungeun Won, Peter Sun, Edita Aksamitiene, Marina Marjanovic, Eric Chaney, Thanh Huong Nguyen, J. Gary Eden, Stephen Boppart

Proceedings Volume PC12358, PC1235809 (2023) https://doi.org/10.1117/12.2648469

KEYWORDS: Ear, Chemical mechanical planarization, Optical coherence tomography, In vitro testing, Injuries, Animal model studies, Tissues, Resistance, Medicine, Instrument modeling

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Proceedings Article | 15 March 2023 Presentation

Characterization of Chinese hamster ovary (CHO) cell lines by simultaneous label-free autofluorescence multi-harmonic (SLAM) microscopy for upstream bioprocessing (Conference Presentation)

Alexander Ho, Jindou Shi, Eric Chaney, Corey Snyder, Aneesh Alex, Remben Talaban, Janet Sorrells, Darold Spillman, Marina Marjanovic, Steve Hood, Stephen Boppart

Proceedings Volume PC12383, PC1238302 (2023) https://doi.org/10.1117/12.2646378

KEYWORDS: Microscopy, Ovary, Image processing, Luminescence, Image segmentation, Third-harmonic generation, Second-harmonic generation, Proteins, Multimodal imaging, Manufacturing

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Proceedings Article | 6 March 2023 Presentation

Machine learning-assisted label-free multimodal optical bioimaging for biopharmaceutical CHO cell line characterization

Jindou Shi, Alexander Ho, Corey Snyder, Eric Chaney, Janet Sorrells, Aneesh Alex, Remben Talaban, Darold Spillman, Marina Marjanovic, Steve Hood, Stephen Boppart

Proceedings Volume PC12371, PC123710D (2023) https://doi.org/10.1117/12.2648499

KEYWORDS: Microscopy, Image segmentation, Fluorescence lifetime imaging, Feature extraction, Biomedical optics, Therapeutic antibodies, Proteins, Profiling, Ovary, Neural networks

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Showing 5 of 10 publications

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