Koji Sugioka is a senior research scientist at RIKEN – Advanced Science Institute and a guest professor at Tokyo University of Science and Tokyo Denki University. He received B.E., M.E. and Ph.D degrees in electronics form Waseda University in 1984, 1986 and 1993, respectively.
Sugioka joined RIKEN in 1986. At RIKEN, he has worked on doping, etching and deposition of semiconductors and surface modification of metals by using excimer lasers. He also studied on microfabrication of hard materials like glass by using VUV and ultrafast lasers. His current interests center on the development of advanced laser microprocessing techniques for performing surface and 3-D microstructuring of transparent materials, with applications to lab-on-a-chip, photonic and electronic devices.
Sugioka has received eight awards for his research, inventions and contributions in the area of laser microprocessing. He published more than 130 articles, gave more than 80 invited talks at international conferences and about 90 invited talks at domestic conferences, and has about 30 patents or pending patents.
Sugioka served as a conference chair, co-chair, and committee member for numerous international conferences. He is also editor-in-chief of the Laser Micro/Nanoengineering.
Sugioka joined RIKEN in 1986. At RIKEN, he has worked on doping, etching and deposition of semiconductors and surface modification of metals by using excimer lasers. He also studied on microfabrication of hard materials like glass by using VUV and ultrafast lasers. His current interests center on the development of advanced laser microprocessing techniques for performing surface and 3-D microstructuring of transparent materials, with applications to lab-on-a-chip, photonic and electronic devices.
Sugioka has received eight awards for his research, inventions and contributions in the area of laser microprocessing. He published more than 130 articles, gave more than 80 invited talks at international conferences and about 90 invited talks at domestic conferences, and has about 30 patents or pending patents.
Sugioka served as a conference chair, co-chair, and committee member for numerous international conferences. He is also editor-in-chief of the Laser Micro/Nanoengineering.
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Fs-LDW is a promising technique for fine 3D printing of biomaterials such as protein due to nonlinear multiphoton absorption processes facilitating localized microfabrication along a designated laser light path. The use of protein as a precursor material for fs-LDW is attractive because the fabricated structures retain their native functions as demonstrated by several reports. These reports range over various combination of protein and photoactivators, but pure protein can also be utilized as a precursor. The resulting proteinaceous microstructures with native function retained and submicron feature sizes might offer diverse biomedical or biochip applications.
This work highlights the capabilities of fs-LDW from pure protein with a biologically highly regarded protein, broadening the scope of the 3D printing technology as well as providing a new use for the fluorescent protein family.
3D glass nanofluidics fabricated by femtosecond laser processing for study on cancer cell metastasis
Ultrashort pulse GHz burst mode laser ablation at different wavelengths for surface microfabrication
Rapid prototyping by ultrafast lasers which induces local modifications inside transparent materials of both glass and polymers with high precision at micro- and nanoscale is a promising tool for fabrication of such biochips. We have developed a new technology by combining subtractive ultrafast laser assisted chemical etching of glasses and additive two-photon polymerization to integrate 3D glass microfluidics and polymer microcomponents in a single biochip. The innovative hybrid "ship-in-a-bottle" approach is not only an instrument that can tailor 3D environments but also a tool to fabricate biomimetic in vivo structures inside a glass microfluidic chip. It was possible to create appropriate environment for cell culturing and to offer robustness and transparency for optical interrogation. Cancer cells were cultivated inside biochips and monitored over short and long periods. With the view of understanding cancer cells specific behavior such as migration or invasiveness inside human body, introduction of different geometrical configurations and chemical conditions were proposed. The cells were found responsive to a gradient of nutrient concentration through the microchannels of a 3D polymeric scaffold integrated inside glass biochip.
Femtosecond laser 3D micromachining and its applications to biochip fabrication (Presentation Video)
Characterization of fused silica ablation by F2-KrF excimer laser multiwavelength excitation process
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