Prof. Rinat O. Esenaliev Profile

Prof. Rinat O. Esenaliev

Professor at Univ of Texas Medical Branch

SPIE Involvement:

Conference Program Committee | Author

Publications (85)

Proceedings Article | 13 March 2024 Poster

Nano-pulsed laser therapy (NPLT) for clearance of AD-related toxic oligomers

Kevin Johnson, Auston Grant, Kathia Johnson, Rinat Esenaliev, Giulio Taglialatela, Maria-Adelaide Micci

Proceedings Volume PC12842, PC1284225 (2024) https://doi.org/10.1117/12.3008996

KEYWORDS: Laser therapeutics, Traumatic brain injury, Optoacoustics, Stem cells, Neurons, Alzheimer disease

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Proceedings Article | 12 March 2024 Paper

Wearable, high-resolution sensors for noninvasive monitoring of physiologic variables

Rinat Esenaliev

Proceedings Volume 12838, 1283805 (2024) https://doi.org/10.1117/12.3008173

KEYWORDS: Optoacoustics, Tissues, Blood, Glucose, Oxygenation, Optical coherence tomography, Optical sensing, Biomedical optics, In vivo imaging, Biological imaging

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Proceedings Article | 16 March 2023 Presentation

Water monitoring in tissues with high-resolution optoacoustic technique (Conference Presentation)

Rinat Esenaliev

Proceedings Volume PC12393, PC1239306 (2023) https://doi.org/10.1117/12.2655557

KEYWORDS: Tissues, Optoacoustics, Skin, Ultrasonography, Tissue optics, Signal generators, Scattering, In vivo imaging, In vitro testing, Diagnostics

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Proceedings Article | 7 March 2022 Poster

High-resolution optoacoustic and ultrasound techniques for water monitoring in tissues

Sergei Perkov, Dmitry Gorin, Rinat Esenaliev

Proceedings Volume PC11960, PC119601T (2022) https://doi.org/10.1117/12.2612420

KEYWORDS: Tissues, Optoacoustics, Ultrasonography, Skin, In vivo imaging, Diagnostics, Chromophores

Proceedings Article | 2 March 2022 Presentation

Ultra-fast, ultra-sensitive single molecule detection and real-time imaging

Pavel Melentiev, Rinat Esenaliev, Lina Son, Denis Kudryavtsev, Igor Kasheverov, Victor Tsetlin, Victor Balykin

Proceedings Volume PC11967, PC1196709 (2022) https://doi.org/10.1117/12.2617863

KEYWORDS: Molecules, Ultrafast phenomena, Real time imaging, Imaging systems, Motion measurement, Viruses, Luminescence, Infrared imaging, Image resolution, Data acquisition

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Proceedings Article | 9 March 2021 Presentation

Nano-pulsed laser therapy of abnormal hippocampal neurogenesis after traumatic brain injury

Emanuele Mocciaro, Rinat Esenaliev, Stacey Sell, Irene Petrov, Yuriy Petrov, Elizabeth Bishop, Kathia Johnson, Donald Prough, Maria-Adelaide Micci

Proceedings Volume 11642, 116422J (2021) https://doi.org/10.1117/12.2584191

KEYWORDS: Traumatic brain injury, Laser therapeutics, Neurogenesis, Optoacoustics

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Proceedings Article | 5 March 2021 Poster

Noninvasive, accurate optoacoustic monitoring of water content in tissues

Sergei Perkov, Dmitry Gorin, Rinat Esenaliev

Proceedings Volume 11642, 116424N (2021) https://doi.org/10.1117/12.2584188

KEYWORDS: Tissues, Optoacoustics, Skin, Diagnostics

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Proceedings Article | 5 March 2021 Poster

Optoacoustic staging, monitoring, and imaging of hematomas

Sergei Perkov, Oleg Grishin, Rinat Esenaliev, Simon Powell, Evgeny Shirshin, Vasiliy Chernyshev, Dmitry Gorin

Proceedings Volume 11642, 116423Z (2021) https://doi.org/10.1117/12.2584189

KEYWORDS: Optoacoustics, Tissues, Skin, Neuroimaging, Brain, Absorption

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Proceedings Article | 28 August 2019 Paper

Fiber-optic probes for biomedical optoacoustic imaging, monitoring, and sensing

Rinat Esenaliev

Proceedings Volume 11199, 111990W (2019) https://doi.org/10.1117/12.2539195

KEYWORDS: Optoacoustics, Biomedical optics, Tissues, Blood, Patents, Fiber optics, Ultrasonography, Pulsed laser operation, Laser vision correction, Real time imaging

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Proceedings Article | 18 March 2019 Paper

25 years of biomedical optoacoustics: From idea to optoacoustic imaging and theranostics

Rinat Esenaliev

Proceedings Volume 10878, 108780U (2019) https://doi.org/10.1117/12.2511785

KEYWORDS: Optoacoustics, Tissues, Signal detection, Tumors, Biomedical optics, Blood, Traumatic brain injury, Diagnostics, Signal attenuation, Tissue optics

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Proceedings Article | 28 March 2018 Paper

Optoacoustic theranostics

Irene Petrov, Maria-Adelaide Micci, Donald Prough, Yuriy Petrov, Jutatip Guptarak, Auston Grant, Margaret Parsley, Ian Bolding, Rinat Esenaliev

Proceedings Volume 10494, 104941F (2018) https://doi.org/10.1117/12.2294053

KEYWORDS: Diagnostics, Traumatic brain injury, Tissues, Ultrasonography, Hypoxia, Phototherapy, Photoacoustic spectroscopy, Laser therapeutics, Tissue optics, Low level phototherapy

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Proceedings Article | 22 March 2018 Paper

Noninvasive measurement of cerebral venous oxygenation in neonates with a multi-wavelength, fiber-coupled laser diode optoacoustic system

Stephen Herrmann, Irene Petrov, Yuriy Petrov, Rafael Fonseca, C. Joan Richardson, Ekaterina Shanina, Donald Prough, Rinat Esenaliev

Proceedings Volume 10494, 1049409 (2018) https://doi.org/10.1117/12.2294057

KEYWORDS: Hypoxia, Fiber coupled lasers, Diodes, Laser systems engineering, Photoacoustic spectroscopy, Semiconductor lasers, Cardiovascular surgery, Traumatic brain injury, Veins, Laser development

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Proceedings Article | 27 March 2017 Paper

Simultaneous measurements of total hemoglobin concentration and blood oxygenation with laser diode-based optoacoustic system

Irene Petrov, Donald Prough, Yuriy Petrov, S. Nan Henkel, Roger Seeton, Rinat Esenaliev

Proceedings Volume 10064, 100640P (2017) https://doi.org/10.1117/12.2256169

KEYWORDS: Blood, Semiconductor lasers, Laser systems engineering, Photoacoustic spectroscopy, Fiber coupled lasers, Blood vessels, Arteries, Human subjects, Functional imaging, Skin, Tissues, Laser development, Imaging systems, Tissue optics

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Proceedings Article | 22 March 2017 Paper

Optoacoustic mapping of cerebral blood oxygenation in humans

Yuriy Petrov, Donald Prough, Irene Petrov, C. Joan Richardson, Rafael Fonseca, Claudia Robertson, Rinat Esenaliev

Proceedings Volume 10064, 100640A (2017) https://doi.org/10.1117/12.2256167

KEYWORDS: Signal detection, Brain mapping, Blood, Tissues, Photoacoustic spectroscopy, Traumatic brain injury, Near infrared, Blood vessels, Skull, Functional imaging, Diagnostics, Head, Semiconductor lasers, Imaging systems, Laser systems engineering, Neuroscience

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Proceedings Article | 22 March 2017 Paper

Cerebral blood oxygenation measurements in neonates with optoacoustic technique

Stephen Herrmann, Irene Petrov, Yuriy Petrov, C. Joan Richardson, Rafael Fonseca, Donald Prough, Rinat Esenaliev

Proceedings Volume 10064, 100640Q (2017) https://doi.org/10.1117/12.2256170

KEYWORDS: Signal detection, Blood, Semiconductor lasers, Skull, Photoacoustic spectroscopy, Hypoxia, Veins, Laser development, Laser systems engineering, Computer simulations, Imaging systems, Reflection, Optical parametric oscillators, Skin

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Proceedings Article | 18 March 2016 Paper

Optoacoustic measurements of human placenta and umbilical blood oxygenation

T. Nanovskaya, I. Petrov, Y. Petrov, S. Patrikeeva, M. Ahmed, G. Hankins, D. Prough, R. Esenaliev

Proceedings Volume 9708, 97080N (2016) https://doi.org/10.1117/12.2218923

KEYWORDS: Fetus, Blood, Oxygen, Tissues, Carbon dioxide, Veins, Diagnostics, Technologies and applications, Signal detection, Blood vessels, Ultrasonography, Calibration

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Proceedings Article | 18 March 2016 Paper

Transmission (forward) mode, transcranial, noninvasive optoacoustic measurements for brain monitoring, imaging, and sensing

Irene Petrov, Yuriy Petrov, Donald Prough, C. Joan Richardson, Rafael Fonseca, Claudia Robertson, C. Vasantha Asokan, Adaeze Agbor, Rinat Esenaliev

Proceedings Volume 9708, 97084P (2016) https://doi.org/10.1117/12.2218919

KEYWORDS: Signal detection, Traumatic brain injury, Tissues, Transducers, Head, Blood, Neuroimaging, Brain, Fiber optics, Acoustics, Semiconductor lasers, Laser systems engineering, Sensors, Imaging systems

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Proceedings Article | 17 March 2015 Paper

Noninvasive, optoacoustic detection and characterization of intra- and extracranial hematomas and cerebral hypoxia

Andrey Petrov, Donald Prough, Yuriy Petrov, Irene Petrov, Claudia Robertson, Vasantha Asokan, Adaeze Agbor, Rinat Esenaliev

Proceedings Volume 9323, 93233N (2015) https://doi.org/10.1117/12.2085080

KEYWORDS: Blood, Traumatic brain injury, Signal detection, Hypoxia, Diagnostics, Ultrasonography, Medicine, Near infrared spectroscopy, Light scattering, Near infrared

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Proceedings Article | 11 March 2015 Paper

Monitoring cerebral venous blood oxygenation in neonates with a medical-grade optoacoustic system

Irene Petrov, Rafael Fonseca, C. Richardson, Yuriy Petrov, Donald Prough, Andrey Petrov, Karon Wynne, Stephan Westermann, Rinat Esenaliev

Proceedings Volume 9323, 932302 (2015) https://doi.org/10.1117/12.2085076

KEYWORDS: Blood, Signal detection, Reflection, Hypoxia, Imaging systems, Skin, Blood vessels, Brain imaging, Tomography, Tissues

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Proceedings Article | 3 March 2014 Paper

Optoacoustic measurement of central venous oxygenation for assessment of circulatory shock: clinical study in cardiac surgery patients

Irene Petrov, Donald Prough, Michael Kinsky, Yuriy Petrov, Andrey Petrov, S. Nan Henkel, Roger Seeton, Michael Salter, Rinat Esenaliev

Proceedings Volume 8943, 89430Y (2014) https://doi.org/10.1117/12.2045356

KEYWORDS: Blood, Ultrasonography, Surgery, Oxygen, Tissues, Imaging systems, Veins, Arteries, Skin, Blood circulation

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Proceedings Article | 3 March 2014 Paper

Optoacoustic detection and monitoring of blast-induced intracranial hematomas in rats

Andrey Petrov, Karon Wynne, Donald Prough, Douglas Dewitt, Yuriy Petrov, Irene Petrov, Margaret Parsley, Rinat Esenaliev

Proceedings Volume 8943, 894350 (2014) https://doi.org/10.1117/12.2045357

KEYWORDS: Traumatic brain injury, Blood, Injuries, Brain, Magnetic resonance imaging, Head, Tissues, Skin, Blood pressure, Computed tomography

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Proceedings Article | 3 March 2014 Paper

Optoacoustic monitoring of central and peripheral venous oxygenation during simulated hemorrhage

Andrey Petrov, Michael Kinsky, Donald Prough, Yuriy Petrov, Irene Petrov, S. Nan Henkel, Roger Seeton, Michael Salter, Muzna Khan, Rinat Esenaliev

Proceedings Volume 8943, 894336 (2014) https://doi.org/10.1117/12.2045358

KEYWORDS: Blood, Veins, Ultrasonography, Skin, Heart, Blood pressure, Blood circulation, Optical parametric oscillators, Brain, Liver

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Proceedings Article | 4 March 2013 Paper

Noninvasive optoacoustic system for rapid diagnosis and management of circulatory shock

Irene Petrov, Michael Kinsky, Yuriy Petrov, Andrey Petrov, S. Henkel, Roger Seeton, Rinat Esenaliev, Donald Prough

Proceedings Volume 8581, 85814Y (2013) https://doi.org/10.1117/12.2010434

KEYWORDS: Blood, Ultrasonography, Veins, Tissues, Skin, Heart, Blood circulation, Oxygen, Interfaces, Absorption

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Proceedings Article | 4 March 2013 Paper

Cerebral venous blood oxygenation monitoring during hyperventilation in healthy volunteers with a novel optoacoustic system

Andrey Petrov, Donald Prough, Irene Petrov, Yuriy Petrov, Donald Deyo, Sheryl Henkel, Roger Seeton, Rinat Esenaliev

Proceedings Volume 8581, 85814Z (2013) https://doi.org/10.1117/12.2010438

KEYWORDS: Blood, Traumatic brain injury, Near infrared spectroscopy, Hypoxia, Brain, Veins, Absorption, Oxygen, Tissues, Head

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Proceedings Article | 28 February 2012 Paper

Novel optoacoustic system for noninvasive continuous monitoring of cerebral venous blood oxygenation

Yuriy Petrov, Irene Petrov, Donald Prough, Rinat Esenaliev

Proceedings Volume 8223, 82231L (2012) https://doi.org/10.1117/12.914650

KEYWORDS: Blood, Traumatic brain injury, Veins, Signal detection, Algorithm development, Spinal cord, Injuries, Brain, Absorption, Blood vessels

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Proceedings Article | 28 February 2012 Paper

Noninvasive optoacoustic system for rapid diagnostics and management of circulatory shock

Rinat Esenaliev, Irene Petrov, Yuriy Petrov, Michael Kinsky, Donald Prough

Proceedings Volume 8223, 82230F (2012) https://doi.org/10.1117/12.914653

KEYWORDS: Blood, Ultrasonography, Imaging systems, Veins, Blood vessels, Algorithm development, Skin, Diagnostics, Heart, Interfaces

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Circulatory shock is lethal, if not promptly diagnosed and effectively treated. Typically, circulatory shock resuscitation is guided by blood pressure, heart rate, and mental status, which have poor predictive value. In patients, in whom early goaldirected therapy was applied using central venous oxygenation measurement, a substantial reduction of mortality was reported (from 46.5% to 30%). However, central venous catheterization is invasive, time-consuming and often results in complications. We proposed to use the optoacoustic technique for noninvasive, rapid assessment of central venous oxygenation. In our previous works we demonstrated that the optoacoustic technique can provide measurement of blood oxygenation in veins and arteries due to high contrast and high resolution. In this work we developed a novel optoacoustic system for noninvasive, automatic, real-time, and continuous measurement of central venous oxygenation. We performed pilot clinical tests of the system in human subjects with different oxygenation in the internal jugular vein and subclavian vein. A novel optoacoustic interface incorporating highly-sensitive optoacoustic probes and standard ultrasound imaging probes were developed and built for the study. Ultrasound imaging systems Vivid i and hand-held Vscan (GE Healthcare) as well as Site-Rite 5 (C.R. Bard) were used in the study. We developed a special algorithm for oxygenation monitoring with minimal influence of overlying tissue. The data demonstrate that the system provides precise measurement of venous oxygenation continuously and in real time. Both current value of the venous oxygenation and trend (in absolute values and for specified time intervals) are displayed in the system. The data indicate that: 1) the optoacoustic system developed by our group is capable of noninvasive measurement of blood oxygenation in specific veins; 2) clinical ultrasound imaging systems can facilitate optoacoustic probing of specific blood vessels; 3) the optoacoustic system provides noninvasive monitoring during rapid changes in blood oxygenation.

Proceedings Article | 28 February 2012 Paper

Noninvasive optoacoustic monitoring of cerebral venous blood oxygenation in newborns

Irene Petrov, Karon Wynne, Yuriy Petrov, Rinat Esenaliev, C. Joan Richardson, Donald Prough

Proceedings Volume 8223, 82231M (2012) https://doi.org/10.1117/12.914657

KEYWORDS: Blood, Ischemia, Signal detection, Brain, Skin, Skull, Software development, Semiconductor lasers, Veins, Data acquisition

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Proceedings Article | 28 February 2011 Paper

Focused, wide-band, polymer-based optoacoustic transducers for noninvasive monitoring of total hemoglobin concentration and other blood variables

Emanuel Saerchen, Irene Petrov, Yuriy Petrov, Donald Prough, Walter Neu, Rinat Esenaliev

Proceedings Volume 7899, 78994E (2011) https://doi.org/10.1117/12.879490

KEYWORDS: Transducers, Blood, Arteries, Blood vessels, Veins, Signal detection, Tissues, In vivo imaging, Ultrasonography, Polymers

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Proceedings Article | 28 February 2011 Paper

High-resolution ultrasound imaging and noninvasive optoacoustic monitoring of blood variables in peripheral blood vessels

Irene Petrov, Yuriy Petrov, Donald Prough, Rinat Esenaliev

Proceedings Volume 7899, 78990B (2011) https://doi.org/10.1117/12.879470

KEYWORDS: Veins, Ultrasonography, Blood, Temperature metrology, Skin, Blood vessels, Oximeters, Arteries, Blood circulation, Imaging systems

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Proceedings Article | 28 February 2011 Paper

Optoacoustic technique for noninvasive monitoring of endotracheal tube placement and positioning

Donald Prough, Yuriy Petrov, Irene Petrov, Michael Kinsky, Rinat Esenaliev

Proceedings Volume 7899, 78990G (2011) https://doi.org/10.1117/12.879474

KEYWORDS: Esophagus, Lung, In vitro testing, Tissues, Near infrared, Laser scattering, Fiber optics, Chest, Radiography, Skin

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Proceedings Article | 28 February 2011 Paper

Combination of optoacoustics and ultrasound imaging for non-invasive, rapid assessment, and management of circulatory shock

Yuriy Petrov, Irene Petrov, Rinat Esenaliev, Michael Kinsky, Donald Prough

Proceedings Volume 7899, 78990C (2011) https://doi.org/10.1117/12.879468

KEYWORDS: Ultrasonography, Veins, Blood, Imaging systems, Blood vessels, Algorithm development, Human subjects, Skin, Arteries, Doppler effect

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Proceedings Article | 26 February 2010 Paper

Novel focused optoacoustic transducers for accurate monitoring of total hemoglobin concentration and oxyhemoglobin saturation: pre-clinical and clinical tests

Emanuel Särchen, Irina Petrova, Yuriy Petrov, Donald Prough, Walter Neu, Rinat Esenaliev

Proceedings Volume 7564, 75641I (2010) https://doi.org/10.1117/12.847084

KEYWORDS: Transducers, Arteries, Signal detection, Veins, Blood, Blood vessels, Semiconductor lasers, Ultrasonography, Absorption, Acoustics

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Proceedings Article | 26 February 2010 Paper

Noninvasive optoacoustic monitoring platform: clinical studies

Rinat Esenaliev, Yuriy Petrov, Irina Petrova, Michael Kinsky, Roger Seeton, Nan Henkel, Donald Prough

Proceedings Volume 7564, 75641H (2010) https://doi.org/10.1117/12.847087

KEYWORDS: Arteries, Blood, Veins, Absorption, Laser systems engineering, Semiconductor lasers, Signal attenuation, Oxygen, Blood vessels, Tissue optics

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Proceedings Article | 25 February 2009 Paper

Clinical tests of highly portable 2-lb. laser diode-based noninvasive optoacoustic hemoglobin monitor

Irina Petrova, Yuriy Petrov, Donald Prough, Rinat Esenaliev

Proceedings Volume 7177, 717705 (2009) https://doi.org/10.1117/12.816005

KEYWORDS: Arteries, Semiconductor lasers, Algorithm development, Blood, Skin, Blood vessels, Signal to noise ratio, Imaging systems, Human subjects, Transducers

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Proceedings Article | 25 February 2009 Paper

Clinical tests of noninvasive optoacoustic cerebral venous oxygenation monitoring system

Y. Petrov, I. Petrova, R. Esenaliev, D. Prough

Proceedings Volume 7177, 717706 (2009) https://doi.org/10.1117/12.816015

KEYWORDS: Blood, Absorption, Tissues, Traumatic brain injury, In vivo imaging, Near infrared spectroscopy, Signal detection, Tissue optics, Brain, Oximetry

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Proceedings Article | 25 February 2009 Paper

Novel optoacoustic array for noninvasive monitoring of blood parameters

Valeriy Andreev, Yuriy Petrov, Donald Prough, Irina Petrova, Rinat Esenaliev

Proceedings Volume 7177, 71770O (2009) https://doi.org/10.1117/12.816043

KEYWORDS: Blood, Signal detection, Chemical elements, Prisms, Arteries, In vitro testing, Absorption, In vivo imaging, Blood vessels, Acoustics

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SPIE Journal Paper | 1 March 2008 Open Access

Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Veronika Sapozhnikova, Roman Kuranov, Inga Cicenaite, Rinat Esenaliev, Donald Prough

JBO, Vol. 13, Issue 02, 021112, (March 2008) https://doi.org/10.1117/12.10.1117/1.2909671

KEYWORDS: Optical coherence tomography, Glucose, Skin, Blood, Tissue optics, Tissues, In vivo imaging, Biomedical engineering, Optical sensing, Biomedical optics

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Proceedings Article | 12 March 2007 Paper

Optoacoustic imaging of blood vessels

I. Patrikeev, H. Brecht, Y. Petrov, I. Petrova, D. Prough, R. Esenaliev

Proceedings Volume 6513, 65130R (2007) https://doi.org/10.1117/12.711176

KEYWORDS: Blood vessels, Monte Carlo methods, Blood, Transducers, Ultrasonography, Veins, Absorption, Arteries, Visualization, Tissues

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